4039-00-3 Usage
Uses
Used in Pharmaceutical Industry:
7-chloro-4-(4-(3-(piperazin-1-yl)propyl)piperazin-1-yl)quinoline is used as an active pharmaceutical ingredient (API) for the development of new drugs targeting various medical conditions. Its unique structure and functional groups make it a promising candidate for the treatment of diseases such as malaria, where it may exhibit antimalarial properties by interfering with the physiological functions of the parasite.
Used in Antimalarial Applications:
7-chloro-4-(4-(3-(piperazin-1-yl)propyl)piperazin-1-yl)quinoline is used as an antimalarial agent, potentially disrupting the food vacuole membrane of the trophozoites, leading to autophagocytosis of the parasites. This mechanism of action could provide an effective treatment option for individuals suffering from malaria, a disease caused by Plasmodium parasites transmitted through the bite of infected mosquitoes.
Used in Drug Development Research:
In addition to its direct application as an antimalarial agent, 7-chloro-4-(4-(3-(piperazin-1-yl)propyl)piperazin-1-yl)quinoline can also be used in drug development research. Its structural features may serve as a starting point for the design and synthesis of new compounds with improved pharmacological properties, potentially leading to the discovery of novel therapeutic agents for a range of diseases.
Used in Chemical Synthesis:
7-chloro-4-(4-(3-(piperazin-1-yl)propyl)piperazin-1-yl)quinoline can also be utilized as a key intermediate in the synthesis of other complex organic molecules, particularly those with potential applications in the pharmaceutical, agrochemical, or materials science industries. Its unique structure and functional groups make it a valuable building block for the development of new molecules with tailored properties and improved performance.
Check Digit Verification of cas no
The CAS Registry Mumber 4039-00-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,0,3 and 9 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4039-00:
(6*4)+(5*0)+(4*3)+(3*9)+(2*0)+(1*0)=63
63 % 10 = 3
So 4039-00-3 is a valid CAS Registry Number.
4039-00-3Relevant academic research and scientific papers
Synthesis and characterization of impurities present in an antimalarial drug piperaquine phosphate
Bhovi, Manjunath G.,Tanwar, Pooja,Yadav, Gyan Chand
, p. 215 - 220 (2011/12/15)
Six impurities formed during the process development of piperaquine phosphate, were identified as 7-chloro-4-(piperazine-1-yl) quinoline A, 3-(4-(7-chloroquinolin-4-yl) piperazine-1-yl) propan-1-ol B, 7-chloro-4-(4-(3-ethoxypropyl) piperazine-1-yl) quinoline C, 1,4-bis (7-chloro-4-quinolinyl) piperazine D, 7-chloro-4-(4-{3- [(7-chloro quinolin-4-yl) oxy] propyl} piperazine-1-yl) quinoline E and 4,4'-[piperazine-1,4-diyl] bis (propane-3,1-diylpiperazine - 4,1-diyl)] bis (7-chloroquinoline) F by LC-MS. The structures of these impurities were further confirmed by synthesis. HPLC analysis of piperaquine phosphate API showed impurities ranging from 0.05 to 0.22%.
