40398-28-5Relevant articles and documents
Reactivity of 1,2,3-triazole-substituted 1-azabutadienes (vinamidines)
Batori, Sandor,Bokotey, Sandor,Messmer, Andras
, p. 146 - 162 (2013/09/24)
The reactivity of the new 1,2,3-triazole-substituted vinamidines (i.e. 1-azabutadienes) was investigated. They were used as synthons to obtain new pyrazole, di-1,2,3-triazole as well as 4-amino-1,2,3-triazole derivatives. The Diels-Alder reaction with inverse electronic demand (using dimethyl 1,2,4,5-tetrazin-3,6-dicarboxylate as reagent) resulted in the formation of a new pyridazine derivative. ARKAT-USA Inc.
PEPTIDIC COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS
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Page 83-84, (2010/11/30)
The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
Novel compounds useful as reversible inhibitors of cysteine proteases
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, (2008/06/13)
Disclosed are novel cathepsin S, K, F, L and B reversible inhibitory compounds of the formula (Ia) and (Ib) where R2, R3, R4, R5, R6, R7, R8, Het and X are defined herein. The co