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404-42-2

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404-42-2 Usage

General Description

2,4'-Difluoroacetanilide is a chemical compound with the molecular formula C8H7F2NO. It is a white crystalline solid with a melting point of 69-71°C. 2,4'-Difluoroacetanilide is used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. It is also used as an intermediate in the manufacture of dyes and pigments. 2,4'-Difluoroacetanilide is an aromatic amide and contains two fluorine atoms, which contribute to its chemical and physical properties. It is important to handle this chemical with caution and in accordance with safety guidelines due to its potential health hazards.

Check Digit Verification of cas no

The CAS Registry Mumber 404-42-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 4 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 404-42:
(5*4)+(4*0)+(3*4)+(2*4)+(1*2)=42
42 % 10 = 2
So 404-42-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H7F2NO/c9-5-8(12)11-7-3-1-6(10)2-4-7/h1-4H,5H2,(H,11,12)

404-42-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-fluoro-N-(4-fluorophenyl)acetamide

1.2 Other means of identification

Product number -
Other names ACETANILIDE,2,4'-DIFLUORO

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:404-42-2 SDS

404-42-2Downstream Products

404-42-2Relevant articles and documents

Use of 3-[18F]fluoropropanesulfonyl chloride as a prosthetic agent for the radiolabelling of amines: Investigation of precursor molecules, labelling conditions and enzymatic stability of the corresponding sulfonamides

Loeser, Reik,Fischer, Steffen,Hiller, Achim,Koeckerling, Martin,Funke, Uta,Maisonial, Aurelie,Brust, Peter,Steinbach, Joerg

supporting information, p. 1002 - 1011 (2013/07/19)

3-[18F]Fluoropropanesulfonyl chloride, a recently proposed prosthetic agent for fluorine-18 labelling, was prepared in a two-step radiosynthesis via 3-[18F]fluoropropyl thiocyanate as an intermediate. Two benzenesulfonate-based radiolabelling precursors were prepared by various routes. Comparing the reactivities of 3-thiocyanatopropyl nosylate and the corresponding tosylate towards [18F]fluoride the former proved to be superior accounting for labelling yields of up to 85%. Conditions for a reliable transformation of 3-[18F]fluoropropyl thiocyanate to the corresponding sulfonyl chloride with the potential for automation have been identified. The reaction of 3-[18F]fluoropropanesulfonyl chloride with eight different aliphatic and aromatic amines was investigated and the identity of the resulting 18F-labelled sulfonamides was confirmed chromatographically by comparison with their nonradioactive counterparts. Even for weakly nucleophilic amines such as 4-nitroaniline the desired radiolabelled sulfonamides were accessible in satisfactory yields owing to systematic variation of the reaction conditions. With respect to the application of the 18F-fluoropropan-sulfonyl group to the labelling of compounds relevant as imaging agents for positron emission tomography (PET), the stability of N-(4-fluorophenyl)-3-fluoropropanesulfonamide against degradation catalysed by carboxylesterase was investigated and compared to that of the analogous fluoroacetamide.

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