40447-11-8

Usage

Uses

Used in Organic Synthesis:
(1-cyclohexyl-3-phenylaziridin-2-yl)(phenyl)methanone is used as a synthetic intermediate for the creation of various complex organic molecules. Its unique structure allows it to serve as a building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (1-cyclohexyl-3-phenylaziridin-2-yl)(phenyl)methanone is used as a compound of interest for drug discovery. Its aziridine core may possess biological activities that could be harnessed for the development of new therapeutic agents, particularly given the potential of aziridines to interact with biological targets in novel ways.
Used in Medicinal Chemistry:
(1-cyclohexyl-3-phenylaziridin-2-yl)(phenyl)methanone is utilized in medicinal chemistry for the exploration of its potential pharmacological properties. (1-cyclohexyl-3-phenylaziridin-2-yl)(phenyl)methanone's structure may allow for the modulation of biological pathways, offering new avenues for the treatment of diseases.
Note: The specific applications listed above are speculative based on the general properties of aziridines and the compound's structure. Actual uses would depend on the outcomes of further research and development.

Upstream product

• 32147-20-9 (Z)-2-bromo-1,3-diphenylprop-2-en-1-one 
• 108-91-8 cyclohexylamine 
• 611-91-6 trans-2,3-dibromo-1,3-diphenylpropan-1-one 
• 611-91-6 2,3-dibromo-1,3-diphenylpropane-1-one 
• 614-47-1 1,3-diphenyl-propen-3-one 

Downstream Products

• 21364-53-4 [3-cyclohexyl-5-((E)-1,2-diphenyl-vinyl)-2-phenyl-2,3-dihydro-oxazol-4-yl]-phenyl-methanone 
• 1196497-29-6 benzyl 1-cyclohexyl-2-methyl-4-phenyl-1H-pyrrole-3-carboxylate 
• 1258314-45-2 benzyl 1-cyclohexyl-2-phenethyl-4-phenyl-1H-pyrrole-3-carboxylate 
• 1196497-31-0 benzyl 1-cyclohexyl-2-ethyl-4-phenyl-1H-pyrrole-3-carboxylate 
• 1258314-44-1 benzyl 2-benzyl-1-cyclohexyl-4-phenyl-1H-pyrrole-3-carboxylate 
• 50743-12-9 1-cyclohexyl-2-phenyl-pyrrole-3,4-dicarboxylic acid dimethyl ester 
• 117835-87-7 (2S,5S)-5-Benzoyl-1-cyclohexyl-2,3-diphenyl-imidazolidin-4-one 
• 117835-89-9 1-Cyclohexyl-5-[1-hydroxy-1-phenyl-meth-(E)-ylidene]-2,3-diphenyl-imidazolidin-4-one 

Relevant academic research and scientific papers

Synthesis of aziridines by electrochemical oxidative annulation of chalcones with primary amines

Synthesis of aziridines by electrochemical oxidative annulation of chalcone 1,3-diphenyl-2-propen-1-one with primary amines has been developed under external oxidant - and base-free conditions. The reaction constitutes a new transformation of chalcones with primary amines to aziridines, providing a complementary, simple, and environmentally friendly approach to the currently available methods. A reaction mechanism for this transformation has been proposed based on the cyclic voltammetry.

I2/TBHP mediated diastereoselective synthesis of spiroaziridines

Eventhough spiroheterocycles are considered as emerging drug candidates, synthesis of spiroaziridines has not been well explored so far. Herein, we disclose an efficient I2/TBHP mediated diastereoselective synthesis of N-alkyl spiroaziridines from primary amines and easily accessible α,β-unsaturated ketones. The reaction is also compatible for the synthesis of 2-aroylaziridines.

A Rapid Synthesis of Aziridine Derivatives over Bentonite in 'Dry Media'

Functionalized aziridines are synthesized from dibromo compounds and primary aliphatic amines in the absence of solvent over bentonite as a solid support; in some examples microwave activation is compared to normal heating.