40473-60-7

Basic information

• Product Name: 2-(1-hydroxy-2-phenylethyl)phenol
• Synonyms: 2-(1-hydroxy-2-phenylethyl)phenol
• CAS NO: 40473-60-7
• Molecular Formula: C₁₄H₁₄O₂
• Molecular Weight: 214
• Mol File: 40473-60-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(1-hydroxy-2-phenylethyl)phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-hydroxy-2-phenylethyl)phenol(40473-60-7)
• EPA Substance Registry System: 2-(1-hydroxy-2-phenylethyl)phenol(40473-60-7)

Safety Data

• Hazardous Substances Data: 40473-60-7(Hazardous Substances Data)

Usage

General Description

2-(1-hydroxy-2-phenylethyl)phenol is a chemical compound with the molecular formula C14H14O2. It is also known as hydroxydopamine and is an organic compound that belongs to the class of phenols. 2-(1-hydroxy-2-phenylethyl)phenol is synthesized by the oxidation of dopamine and has been studied for its potential neurotoxic effects. Additionally, 2-(1-hydroxy-2-phenylethyl)phenol has been investigated for its potential role in the development of Parkinson's disease due to its similar chemical structure to dopamine. Further research is needed to fully understand the biological and toxicological properties of this compound.

Upstream product

• 89-95-2 2-methyl-benzyl alcohol 
• 100-44-7 benzyl chloride 
• 1589-82-8 phenylmagnesium bromide 
• 100-39-0 benzyl bromide 
• 90-02-8 salicylaldehyde 
• 6921-34-2 benzylmagnesium chloride 

Downstream Products

• 18493-15-7 2-[(E/Z)-2-phenylvinyl]phenol 
• 102103-12-8 (2R,4R)-4-Benzyl-2-ethoxy-chroman 
• 102103-12-8 (2S,4R)-4-Benzyl-2-ethoxy-chroman 
• 102103-14-0 (2S,3R,4R)-4-Benzyl-2-ethoxy-3-methyl-chroman 
• 102103-14-0 (2S,3S,4R)-4-Benzyl-2-ethoxy-3-methyl-chroman 
• 87798-97-8 Acetic acid 1-{4-[2-((E)-styryl)-phenoxy]-butyl}-piperidin-3-yl ester 
• 87798-96-7 3-Propoxy-1-{4-[2-((E)-styryl)-phenoxy]-butyl}-piperidine 
• 87798-95-6 3-Ethoxy-1-{4-[2-((E)-styryl)-phenoxy]-butyl}-piperidine 

Relevant articles and documents

A Simple Synthesis of Densely Substituted Benzofurans by Domino Reaction of 2-Hydroxybenzyl Alcohols with 2-Substituted Furans

The Br?nsted acid-catalyzed cascade synthesis of densely substituted benzofurans from easily available salicyl alcohols and biomass-derived furans has been developed. The disclosed sequence includes the intermediate formation of 2-(2-hydroxybenzyl)furans

Cadmium-mediated carbonyl benzylation in tap water

Zn/CdCl2 has been developed as a mediator in the benzylation of various aldehydes in tap water affording the corresponding alcohols in moderate to good yields. The addition of a catalytic amount of InCl3 increases the yield of benzylation product significantly. It can selectively mediate the benzylation of aldehydes in the presence of ketones. A mechanism involving the formation of a cation π-complex is proposed based on the experimental facts. Georg Thieme Verlag Stuttgart.

Silver catalyzed zinc Barbier reaction of benzylic halides in water

Benzylic chlorides react in aqueous dibasic potassium phosphate under silver catalysis with aromatic aldehydes in the presence of zinc dust to give 1,2-diaryl alcohols in moderate to good yields. Dimerization to bibenzyls and reduction of the halide are important side reactions. A wide range of substituted aromatic and heteroaromatic aldehydes and of substituted benzylic chlorides can be used. Aliphatic aldehydes and ketones are unreactive. A mechanism of two SET on the metal surface is discussed.