40484-82-0Relevant academic research and scientific papers
Phosphoric acid-promoted synthesis of 4-acylpyrrole-2-carboxylic esters and dipyrryl ketones from mixed anhydrides
Beshara, Cory S.,Thompson, Alison
, p. 10607 - 10610 (2007/10/03)
An efficient synthesis of 4-acylpyrrole-2-carboxylic esters utilizing a phosphoric acid-catalyzed mixed anhydride system is described. The new route also enables the preparation of dipyrryl ketones and N-confused dipyrryl ketones.
Regioselective pyrrole synthesis from asymmetric β-diketone and conversion to sterically hindered porphyrin
Fujii, Hiroshi,Yoshimura, Tetsuhiko,Kamada, Hitoshi
, p. 1427 - 1430 (2007/10/03)
The condensation of asymmetric β-diketones with α-oximinoacetoacetate esters affords pyrroles regioselectively. The mechanism of the regioselectivity is studied using 13C-NMR spectroscopy. Pyrrole having a neopentyl group at the 4-position is synthesized by the method, and further converted to a steric hindered porphyrin in good yield.
The Chemistry of Pyrrolic Compounds. LXVIII. 13'- and 15'-Methyl Analogues of Deoxophylloerythroetioporphyrin (dpep)
Bong, Ivy C. C.,Clezy, Peter S.,Fookes, Christopher J. R.,Prashar, Jognandan K.,Salek, Abdoreza
, p. 1193 - 1206 (2007/10/02)
A new synthesis of the 13'- and 15'-methyl (1a) analogue of dpep is described commencing with the methylation of phylloerythroetioporphyrin (1d) with subsequent reduction of the derived tertiary alcohol.The availability of this synthetic materials has allowed the presence of this petroporphyrin as its nickel complex to be confirmed in the Julia Creek oil shales.The presence of an isomer of this petroporphyrin has been noted in the same deposit, and the structure of this novel fossil porphyrin has been confirmed as the 15'-methyl analogue (1b) of dpep by a synthesis commencing from the 15'-oxoporphyrin (1e).In addition, the 15'- and 13'-methyl analogues of dpep have been synthesized by cyclization of appropriately substituted propenyl- and isopropenyl-porphyrins respectively.The origin of these two petroporphyrins is discussed.
