40492-33-9

Basic information

• Product Name: 4-((dimethylamino)methyl)-1,3-dioxolan-2-one
• Synonyms: 4-((dimethylamino)methyl)-1,3-dioxolan-2-one
• CAS NO: 40492-33-9
• Molecular Weight: 145.158
• Mol File: 40492-33-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-((dimethylamino)methyl)-1,3-dioxolan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-((dimethylamino)methyl)-1,3-dioxolan-2-one(40492-33-9)
• EPA Substance Registry System: 4-((dimethylamino)methyl)-1,3-dioxolan-2-one(40492-33-9)

Safety Data

• Hazardous Substances Data: 40492-33-9(Hazardous Substances Data)

Upstream product

• 623-57-4 3-(dimethylamino)-1,2-propanediol 
• 124-38-9 carbon dioxide 
• 115-19-5 2-methyl-but-3-yn-2-ol 

Relevant articles and documents

Highly regio- And stereoselective synthesis of cyclic carbonates from biomass-derived polyols: Via organocatalytic cascade reaction

The cascade reaction of CO2, vicinal diols, and propargylic alcohol, was firstly achieved by dual Lewis base (LB) organocatalytic systems involving LB-CO2 adducts and commercially available organic amines. This methodology could overcome the chemical inertness of CO2, providing an alternative route to various functionalized five-membered cyclic carbonates in moderate to high yields under mild reaction conditions (25 °C, 1.0 atm of CO2). More importantly, this method could also be applied for facile and efficient synthesis of chiral polycyclic carbonates from biomass-derived polyols with complete configuration retention of chiral centers. This study provides an environment-friendly, scalable and cost effective protocol to construct value-added cyclic carbonates with multi-functional groups and chiral centers.