404966-42-3

Basic information

• Product Name: Ethanone, 2-(4-chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-
• CAS NO: 404966-42-3
• Molecular Formula: C15H13ClO3S
• Molecular Weight: 308.785
• Mol File: 404966-42-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Ethanone, 2-(4-chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2-(4-chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-(404966-42-3)
• EPA Substance Registry System: Ethanone, 2-(4-chlorophenyl)-1-[4-(methylsulfonyl)phenyl]-(404966-42-3)

Safety Data

• Hazardous Substances Data: 404966-42-3(Hazardous Substances Data)

Upstream product

• 225668-35-9 2-(4-chlorophenyl)-1-[4-(methylthio)phenyl]-1-ethanone 
• 100-68-5 methyl-phenyl-thioether 
• 1878-66-6 4-chlorophenylacetic Acid 

Downstream Products

• 1542256-74-5 5-(4-chlorophenyl)-6-(4-(methylsulfonyl) phenyl)-3-(methylthio)-1,2,4-triazine 
• 1542256-64-3 C₁₅H₁₂ClNO₄S 
• 1542256-69-8 C₁₆H₁₂ClN₃O₂S₂ 
• 877224-37-8 C₁₆H₁₆ClN₃O₃S 
• 877860-39-4 1-[1-(4-chloro-phenyl)-2-(4-methanesulfonyl-phenyl)-2-oxo-ethyl]-1H-pyrrole-2-carboxylic acid methylamide 

Relevant articles and documents

Design, synthesis and in vitro study of 5,6-diaryl-1,2,4-triazine-3-ylthioacetate derivatives as COX-2 and β-amyloid aggregation inhibitors

In order to find novel cyclooxygenase (COX)-2 inhibitors for treating inflammatory-based diseases such as Alzheimer's disease (AD), an ethyl carboxylate side chain was added to 5-(4-chlorophenyl)-6-(4-(methylsulfonyl)phenyl)-3-(methylthio)-1,2,4-triazine

Syntheses of 4,5-diaryl-1,2,3-thiadiazoles

Reaction of thionyl chloride with semicarbazones of 1-(4- methylsulfonylphenyl)-2-(4-substituted pheny)lethanone gave 4-(4- methylsulfonylphenyl)-5-(4-substituted) pheny-1,2,3-thiadiazoles 5. Compounds 5-phenyl-4-(substitutedphenyl)-1,2,3-thiadiazoles 14 were similarly prepared. Chlorosulfonation of the latter followed by ammonia gave the desired compounds 5-(4-aminosulfonylphenyl)-4-(substituted) phenyl-1,2,3-thiadiazoles 6. Copyright Taylor & Francis Inc.