4050-48-0Relevant academic research and scientific papers
Synthesis and characterization of a novel nanomagnetic phase-transfer catalyst and its application to regioselective synthesis of β-azido and β-nitro alcohols in water
Ayashi,Fallah-Mehrjardi,Kiasat
, p. 846 - 852 (2017/08/02)
Immobilization of polyethylene glycol-substituted 1-methylimidazolium bromide on the surface of magnetic Fe3O4 nanoparticles through hexane-1,6-diyldicarbamate linker afforded a powerful and reusable heterogeneous phase-transfer cata
Synthesis and characterization of a novel nano-Fe3O4-copoly[(styrene/acrylic acid)/grafted ethylene oxide and its application as a magnetic and recyclable phase-transfer catalyst in the preparation of β-azido alcohols and β-nitro alc
Kiasat, Ali Reza,Daei, Mina,Saghanezhad, Seyyed Jafar
, p. 581 - 594 (2016/04/26)
A facile method was developed for the synthesis of β-azido alcohols and β-nitro alcohols in the presence of a novel nano-Fe3O4-copoly[(styrene/acrylic acid)/grafted ethylene oxide (nano-Fe3O4-PS-Co-[PAA-g-PEG])
Efficient kinetic bioresolution of 2-nitrocyclohexanol
Milner, Sinead E.,Brossat, Maude,Moody, Thomas S.,Elcoate, Curtis J.,Lawrence, Simon E.,Maguire, Anita R.
experimental part, p. 1011 - 1016 (2010/08/22)
The kinetic bioresolution of 2-nitrocyclohexanol 1 was investigated by screening a range of hydrolases both for enantioselective transesterification and for enantioselective hydrolysis of the corresponding acetate. By appropriate choice of biocatalyst and conditions, both enantiomers of cis and trans 2-nitrocyclohexanol 1 can be accessed in enantiopure form.
Oxidation of azides by the HOF·CH3CN: A novel synthesis of nitro compounds
Carmeli, Mira,Rozen, Shlomo
, p. 4585 - 4589 (2007/10/03)
The HOF·CH3CN complex, readily prepared by passing F 2 through aqueous acetonitrile, is an exceptionally efficient oxygen transfer agent. It is unique in its capacity to oxidize various azides into the corresponding nitro derivatives. This method requires short reactions times and room temperature or below, and the desired nitro compounds were usually isolated in very good yields. The respective nitroso derivatives are believed to be the intermediates in this reaction. Functional groups such as aromatic rings, ketones, nitriles, halides, alcohols, and esters are tolerated. Sulfides react with HOF·CH3CN usually at the same rate as azides. Amines and olefins, however, react faster, so they have to be protected first. Nitro derivatives with various oxygen isotopes can be made using the labeled H 18OF·CH3CN. In the case of chiral azides the stereochemistry around the nitrogen-bonded carbons is retained.
Micellar media for the efficient ring opening of epoxides with CN-, N3-, NO3-, NO2-, SCN-, Cl- and Br- catalyzed with Ce(OTf)4
Iranpoor, Nasser,Firouzabadi, Habib,Shekarize, Marzieh
, p. 724 - 727 (2007/10/03)
Micellar media are introduced for the efficient ring opening of epoxides with sodium salts of nucleophiles such as CN, N3-, NO3-, NO2, SCN, Br and Cl-, catalyzed with Ce(OTf)4. This method is an efficient procedure for the synthesis of different β-substituted alcohols under mild reaction conditions. The reaction with SCN- is an easy procedure for the high yielding preparation of epoxy sulfides.
Synthesis of 2-nitroalcohols by regioselective ring opening of epoxides with MgSO4/MeOH/NaNO2 system: A short synthesis of immunosuppressive agent FTY-720
Kalita,Barua,Bezbarua,Bez
, p. 1411 - 1414 (2007/10/03)
It has been demonstrated that a variety of epoxides can easily be opened with a system consisting of MgSO4/MeOH/NaNO2 giving the corresponding 2-nitroalcohols in excellent yields. This strategy has been applied to achieve a short synthesis of Immunosuppressive Agent FTY - 720.
A new, highly efficient synthesis of conjugated nitrocycloalkenes
Ballini, Roberto,Palestini, Corrado
, p. 5731 - 5734 (2007/10/02)
Sodium borohydride reduction of α-nitrocycloalkanones and successive dehydration of the obtained β-nitroalkanols, by acetylation and dehydroacetylation with basic alumina/DMAP, in refluxing dichloromethane, affords, in one por procedure, conjugated nitrocycloalkenes.
The aluminum amalgam reduction of 2-nitroalkanols promoted by ultrasound
Fitch, Richard W.,Luzzio, Frederick A.
, p. 6013 - 6016 (2007/10/02)
The sonochemical promoted aluminum amalgam reduction of 2-nitroalkanols provides an improved yield and accelerated conversion to the corresponding amino alcohols when compared to the nonultrasound (benchtop) reductions. The appearance of by-product hydrox
Highly selective reduction of 2-nitrocycloalkanones to 2-nitrocycloalkanols with zinc borohydride in DME
Ranu,Das
, p. 2361 - 2362 (2007/10/02)
Clean and efficient reduction of 2-nitrocycloalkanones to 2-nitrocycloalkanols has been achieved using zinc borohydride in 1,2-dimethoxyethane.
A Practical Preparations of Conjugated Nitroalkenes
Jew, Sang-sup,Kim, Hee-doo,Cho, Youn-sang,Cook, Chae-ho
, p. 1747 - 1748 (2007/10/02)
Treatment of alkenes (1a-5a) with sodium nitrite and iodine in ethyl acetate (or ether) and water in the presence of ethylene glycol (or propylene glycol) provides conjugated nitroalkenes (1b-5b) in 49-82percent yields.
