88157-64-6Relevant articles and documents
Efficient kinetic bioresolution of 2-nitrocyclohexanol
Milner, Sinead E.,Brossat, Maude,Moody, Thomas S.,Elcoate, Curtis J.,Lawrence, Simon E.,Maguire, Anita R.
experimental part, p. 1011 - 1016 (2010/08/22)
The kinetic bioresolution of 2-nitrocyclohexanol 1 was investigated by screening a range of hydrolases both for enantioselective transesterification and for enantioselective hydrolysis of the corresponding acetate. By appropriate choice of biocatalyst and conditions, both enantiomers of cis and trans 2-nitrocyclohexanol 1 can be accessed in enantiopure form.