405160-57-8 Usage
Uses
Used in Pharmaceutical Industry:
6-Methoxy-5-(trifluoroMethyl)pyridin-2-aMine is used as a building block for the synthesis of pharmaceuticals. It contributes to the development of biologically active molecules that can be utilized in the creation of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 6-Methoxy-5-(trifluoroMethyl)pyridin-2-aMine is employed as a key component in the production of crop protection agents. Its role in the synthesis of these agents helps to ensure the development of effective solutions for agricultural pest control and crop enhancement.
Used in Research and Development for Medicinal Chemistry:
6-Methoxy-5-(trifluoroMethyl)pyridin-2-amine is utilized in research and development for medicinal chemistry, where it serves as an important intermediate in drug discovery. Its unique structure allows for the exploration of new chemical entities with potential therapeutic applications.
Used in Research and Development for Drug Discovery:
6-Methoxy-5-(trifluoroMethyl)pyridin-2-aMine is also used in drug discovery research, where it plays a crucial role in the synthesis and development of new pharmaceutical agents. Its presence in the molecular structure can influence the pharmacological properties of the resulting compounds, making it a valuable asset in the search for novel treatments.
Overall, 6-Methoxy-5-(trifluoroMethyl)pyridin-2-aMine is a significant intermediate in the production of pharmaceuticals, agrochemicals, and other fine chemicals, playing a vital role in the advancement of various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 405160-57-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,5,1,6 and 0 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 405160-57:
(8*4)+(7*0)+(6*5)+(5*1)+(4*6)+(3*0)+(2*5)+(1*7)=108
108 % 10 = 8
So 405160-57-8 is a valid CAS Registry Number.
405160-57-8Relevant academic research and scientific papers
A practical preparation of methyl 2-methoxy-6-methylaminopyridine-3-carboxylate from 2,6-dichloro-3-trifluoromethylpyridine
Horikawa,Hirokawa,Kato
, p. 1621 - 1627 (2007/10/03)
An effective and practical synthetic route to methyl 2-methoxy-6-methylaminopyridine-3-carboxylate (7), the key intermediate of 5-bromo-2-methoxy-6-methylaminopyridine-3-carboxylic acid (1), from 2,6-dichloro-3-trifluoromethylpyridine (12) was undertaken. Process improvements were highlighted by regioselectivity of 12 with a nitrogen nucleophile and conversion of the 3- trifluoromethyl group into the methoxycarbonyl group. The reaction of 12 with N-benzylmethylamine provided the 6-(N-benzyl-N-methyl)aminopyridine 26a and the regioisomer 26b in >98: 2 ratio in a quantitative yield. Treatment of 2-methoxy-6-methylamino-3-trifluoropyridine (14a) with a large excess of sodium methoxide followed by acid hydrolysis gave the pyridine-3-carboxylic ester 7 in an excellent yield. The potential application of this reaction is also described.
