405198-84-7Relevant academic research and scientific papers
Palladium-Catalyzed Synthesis of 6H-Dibenzo[c,h]chromenes and 5,6-Dihydrobenzo[c]phenanthridines: Application to the Synthesis of Dibenzo[c,h]chromene-6-ones, Benzo[c]phenanthridines, and Arnottin I
Pramanik, Subhendu,Jash, Moumita,Mondal, Debasmita,Chowdhury, Chinmay
, p. 5223 - 5238 (2019/11/11)
6H-Dibenzo[c,h]chromenes and 5,6-dihydrobenzo[c]phenanthridines have been synthesized via Palladium (II)-catalyzed domino reactions of acetylenic substrates involving intramolecular trans-oxo/amino palladation onto the triple bond followed by nucleophilic
Synthesis of N-Heteroaromatic Compounds through Cyclocarbonylative Sonogashira Reactions
Aronica, Laura Antonella,Albano, Gianluigi,Giannotti, Luca,Meucci, Elisa
, p. 955 - 963 (2017/02/15)
A protocol based on cyclocarbonylative Sonogashira reactions has been developed for the synthesis of nitrogen-containing heterocycles. The process is carried out under CO pressure, in the presence of a small amount of PdCl2(PPh3)sub
Synthesis of spiroaminals and spiroketals with bimetallic relay catalysis
Wang, Xianghua,Dong, Shuli,Yao, Zhili,Feng, Lei,Daka, Philias,Wang, Hong,Xu, Zhenghu
supporting information, p. 22 - 25 (2014/01/23)
A novel tandem metal relay catalytic system was developed by combining gold-catalyzed cycloisomerization with an early transition-metal-catalyzed inverse-electron-demand hetero-Diels-Alder (IED-HDA) reaction. Various biologically important spiroaminals an
Formation of indoles, dihydroisoquinolines, and dihydroquinolines by ruthenium-catalyzed heterocyclizations
Varela-Fernández, Alejandro,Varela, Jesús A.,Saá, Carlos
, p. 3285 - 3295 (2013/01/15)
Indoles, dihydroisoquinolines, and dihydroquinolines were efficiently prepared by ruthenium-catalyzed heterocyclizations of aromatic homo- and bis-homopropargyl amines/amides in the presence of an amine/ammonium base-acid pair. These regioselective 5-endo and 6-endo cyclizations most probably occur by nucleophilic trapping of key ruthenium-vinylidene intermediates. Georg Thieme Verlag Stuttgart · New York.
Ruthenium-catalyzed cycloisomerization of aromatic homo- and bis-homopropargylic amines/amides: Formation of indoles, dihydroisoquinolines and dihydroquinolines
Varela-Fernandez, Alejandro,Varela, Jesus A.,Saa, Carlos
supporting information; experimental part, p. 1933 - 1937 (2011/10/08)
Ruthenium-catalyzed cycloisomerizations of aromatic homo- and bis-homopropargylic amines/amides efficiently afford indoles, dihydroisoquinolines and dihydroquinolines. These processes were regioselective (5- and 6-endo cyclizations) on using key Ru vinylidene intermediates. The presence of an amine/ammonium base-acid pair increased the rate of cyclization and facilitated the catalytic turnover. Copyright
Cyclization reactions of 2-alkynylbenzyl alcohol and 2-alkynylbenzylamine derivatives promoted by tetrabutylammonium fluoride
Hiroya, Kou,Jouka, Rumi,Kameda, Mitsuyoshi,Yasuhara, Akito,Sakamoto, Takao
, p. 9697 - 9710 (2007/10/03)
The regioselectivity of the cyclization reaction of 2-ethynylbenzyl alcohol and 2-ethynylbenzylamine derivatives promoted by TBAF was investigated. Six-membered ring derivatives were obtained from the compounds, which have a butyl group on the triple bond. Whereas five-membered ring products were afforded from the substrates having hydrogen or aromatic substituents on the acetylene moiety. It was also concluded that both the tetrabutylammonium cation and fluoride anion were essential for the cyclization. Thus, the actual mechanism and catalytic cycle were also suggested.
