50624-41-4

Upstream product

• 2905-25-1 o-bromobenzenesulfonyl chloride 
• 951885-17-9 2-bromo-N-butylbenzenesulfonamide 
• 405198-84-7 N-[2-[2-(trimethysilyl)ethynyl]benzyl]-(4-methylphenyl)sulfonamide 
• 328088-13-7 N-(2-bromobenzyl)-4-methylbenzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 145782-23-6 N-(2-ethynyl-benzyl)-(4-methylbenzene)sulfonamide 
• 3959-05-5 2-bromobenzylamine 

Relevant academic research and scientific papers

Ruthenium-catalyzed cycloisomerization of aromatic homo- and bis-homopropargylic amines/amides: Formation of indoles, dihydroisoquinolines and dihydroquinolines

Ruthenium-catalyzed cycloisomerizations of aromatic homo- and bis-homopropargylic amines/amides efficiently afford indoles, dihydroisoquinolines and dihydroquinolines. These processes were regioselective (5- and 6-endo cyclizations) on using key Ru vinylidene intermediates. The presence of an amine/ammonium base-acid pair increased the rate of cyclization and facilitated the catalytic turnover. Copyright

Formation of indoles, dihydroisoquinolines, and dihydroquinolines by ruthenium-catalyzed heterocyclizations

Indoles, dihydroisoquinolines, and dihydroquinolines were efficiently prepared by ruthenium-catalyzed heterocyclizations of aromatic homo- and bis-homopropargyl amines/amides in the presence of an amine/ammonium base-acid pair. These regioselective 5-endo and 6-endo cyclizations most probably occur by nucleophilic trapping of key ruthenium-vinylidene intermediates. Georg Thieme Verlag Stuttgart · New York.