405548-29-0Relevant academic research and scientific papers
N-Boc-4-aminopyrazole-5-carbaldehydes in Friendl?nder synthesis of pyrazolo[4,3-b]pyridines
Yakovenko, Georgiy G.,Lukianov, Oleh A.,Bol’but, Andriy V.,Vovk, Mykhailo V.
, p. 379 - 385 (2019)
[Figure not available: see fulltext.] N-Boc-4-aminopyrazole-5-carbaldehydes reacted with aryl, hetaryl, alkyl, and cycloalkyl ketones containing methylene groups. The reactions were accomplished in refluxing acetic acid in the presence of pyrrolidine and resulted in the formation of 5-substituted and carbo[b]fused pyrazolo[4,3-b]pyridines.
A convenient synthesis method of 5-oxopyrazolo[4,3-b]pyridine-6-carboxylic acids and their nitriles
Yakovenko, Georgiy G.,Lukianov, Oleh А.,Bol’but, Andriy V.,Vovk, Mikhailo V.
, p. 1211 - 1216 (2020/01/08)
[Figure not available: see fulltext.] N-Boc-protected 5-formyl-1H-pyrazol-4-amines react with malonic acid in pyridine in the presence of pyrrolidine at 45–50°С or with malonic acid monomethyl ether in the presence of pyrrolidine in AcOH under reflux with
LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF
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Paragraph 00428, (2017/02/24)
Described herein are compounds that are LOXL2 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with LOXL2 activity.
4-ACYLAMINOPYRAZOLE DERIVATIVES
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, (2008/06/13)
A 4-acylaminopyrazole derivative represented by the following general formula: wherein R1 is a hydrogen atom, an optionally substituted C1-C16 alkyl group or the like, ???R2 and R3 are independently a
