4056-56-8

Usage

Uses

Used in Pharmaceutical Research:
N-(4-oxocyclohexa-2,5-dien-1-ylidene)benzenesulfonamide is utilized as a pharmaceutical candidate for its potential antiviral and anticancer properties. Its unique chemical structure allows it to be a subject of interest in the development of new treatments for viral infections and cancer.
Used in Organic Synthesis:
In the field of organic chemistry, N-(4-oxocyclohexa-2,5-dien-1-ylidene)benzenesulfonamide is employed as a reagent in the synthesis of various organic compounds. Its reactivity and stability make it a valuable component in creating a range of chemical products.
Used in Environmental and Health Safety:
While not a direct application, the compound's potential hazards highlight the importance of its use in research aimed at understanding and mitigating environmental and health risks associated with chemical compounds. This includes the development of safe handling procedures and storage methods to prevent accidental exposure or contamination.

Upstream product

• 1678-25-7 N-phenylbenzenesulfonamide 
• 123-30-8 4-amino-phenol 
• 5471-90-9 N-(4-hydroxyphenyl)benzenesulfonamide 
• 98-09-9 benzenesulfonyl chloride 
• 150081-90-6 Dimethyl <2-hydroxy-5-phenyl>phosphonate 

Downstream Products

• 84452-51-7 N-phenylsulfonyl-2-phenylsulfonyl-4-aminophenol 
• 216065-94-0 2-Azido-4-phenylsulfonylamidophenol 
• 331652-77-8 ethyl 2-{5-[(benzenesulfonyl)amino]-2-hydroxy-phenyl}-3-oxobutanoate 
• 5471-90-9 N-(4-hydroxyphenyl)benzenesulfonamide 
• 98-10-2 benzenesulfonamide 
• 76551-73-0 N-(4-Octadecyloxyphenyl)-1,4-benzoquinone Monoimine 
• 488-48-2 tetrabromobenzoquinone 
• 51767-43-2 N-phenylsulfonyl-2-chloro-4-aminophenol 
• 14504-09-7 2,3,5,5,6,6-hexachloro-2-cyclohexene-1,4-dione 
• 62638-01-1 N-benzenesulfonyl-2,6-dibromo-1,4-benzoquinone imine 
• 51767-46-5 N-(3,5-dibromo-4-hydroxyphenyl)benzenesulfonamide 
• 118-75-2 chloranil 

Relevant academic research and scientific papers

Synthesis of 5-substituted 2,3-dihydrobenzofurans in a one-pot oxidation/cyclization reaction

Variously substituted 2,3-dihydrobenzofurans have been synthesized according to a sequential one-pot oxidation/cyclization procedure between para-aminophenol derivatives and an azadiene.

EFFECT OF ARENESULFONAMIDE GROUP ON THE NATURE OF SUBSTITUTION IN THE AROMATIC RING. IV. REACTION OF DERIVATIVES OF 4-SULFONAMIDOPHENOL AND 1,4-DI(SULFONAMIDO)BENZENE WITH NITROSATING AGENTS

The action of nitrosating agents on derivatives of 4-sulfonamidophenol and 1,4-di(sulfonamido)benzene leads to the formation of either the nitration products or the oxidation products.

Reactions of Phosphites with 1,4-Benzoquinone Monoimines

Trimethyl phosphite (2a) reacts with N-(phenylsulfonyl)-1,4-benzoquinone monoimine (1a) to give the respective phosphonate 3c, phosphates 3d, 3e and the alkylated products 3a and 3b.The reaction of triethyl phosphite (2b) with the same quinone imine 1a yi

BROMINATION OF 4-ARENESULFONAMIDOPHENOLS (OR 1-NAPHTHOLS) AND N-ARYLSULFONYL-1,4-BENZO(NAPHTHO)QUINON-4-IMINES

2,3,6-Tribromo-N-phenylsulfonyl-1,4-benzoquinon-4-imines are formed on bromination of 4-arenesulfonamidophenols and N-aryl-sulfonyl-1,4-benzoquinon-4-imines but 2-bromo-N-arylsulfonyl-1,4-naphthoquinon-4-imines are formed from 4-arenesulfonamido-1-naphthols and N-arylsulfonyl-1,4-naphthoquinon-4-imines.

ESR spectra of free radicals derived from N-aryl- and N-sulphonylaryl-1,4-benzoquinone imines

ESR spectra of free radicals from 23 derivatives of 1,4-benzoquinone imines, obtained by electrochemical or chemical reduction of these compounds or by oxidation of the corresponding p-aminophenols, have been studied in solution.In the course of the processes mentioned, anion radicals of 1,4-benzoquinone imines are formed while in the case of reduction of N-sulphonyl derivatives (depending on the potential of electrochemical generation) neutral radicals can be obtained as well.Anion radicals of the corresponding 1,4-benzoquinones are formed in the case of N-arylbenzoquinone imines; they can also be obtained in other cases if the water content in the solution is high enough (apparently as a result of hydrolysis).The pathways of free radical formation and their structural peculiarities are discussed.Neutral free radicals of 1,4-benzoquinone sulphonyldiimines are stable enough to be isolated in the solid phase.The latter are assumed to be of quinoid structure with protonated imine nitrogen.

Preparation of quinone-imide ketals from amides with hypervalent organo-iodine compounds

Iodosylbenzene in methanol in the presence of molecular sieves oxidises amides into quinone-imide mono ketals.

Synthesis of Quinone-Imines with Iodoxybenzene

A new route to quinone-imines by using iodoxybenzene and vanadyl acetylacetonate as a catalyst is described.