1678-25-7

Basic information

• Product Name: Benzenesulfonanilide
• Synonyms: BENZENESULFONANILIDE;N-phenylbenzenesulphonamide;BENZENESULFONANILIDE 98+%;Benzenesulphanilide;N-Phenylbenzolsulfonamid;N-Phenylbenzenesulfonamidebenzenesulfonanilide;N-(Phenylsulfonyl)aniline;N-PHENYLBENZENESULFONAMIDE
• CAS NO: 1678-25-7
• Molecular Formula: C₁₂H₁₁NO₂S
• Molecular Weight: 233.29
• EINECS: 216-832-4
• Product Categories: API intermediates
• Mol File: 1678-25-7.mol
• Article Data: 161

Chemical Properties

• Melting Point: 110°C
• Boiling Point: 220.4°C (rough estimate)
• Flash Point: 184.411 °C
• Appearance: /
• Density: 1.2503 (rough estimate)
• Vapor Pressure: 5.12E-06mmHg at 25°C
• Refractive Index: 1.6000 (estimate)
• Solubility: soluble in Methanol
• PKA: 8.51±0.10(Predicted)
• CAS DataBase Reference: Benzenesulfonanilide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonanilide(1678-25-7)
• EPA Substance Registry System: Benzenesulfonanilide(1678-25-7)

Safety Data

• Safety Statements: 22-24/25
• RTECS: DB3500000
• Hazardous Substances Data: 1678-25-7(Hazardous Substances Data)

Usage

Safety Profile

Questionable carcinogen withexperimental tumorigenic data. When heated todecomposition it emits very toxic fumes of SOx and NOx.

InChI:InChI=1/C12H11NO2S/c14-16(15,12-9-5-2-6-10-12)13-11-7-3-1-4-8-11/h1-10,13H

Upstream product

• 167824-71-7 (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1-[3-(hydroxymethyl)benzyl]-3-(5-hydroxypentyl)-1,3-diazepan-2-one 
• 167824-65-9 ethyl 3-{[(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-3-(5-hydroxypentyl)-2-oxo-1,3-diazepan-1-yl]methyl}benzoate 
• 167824-62-6 (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(5-methoxypentyl)-1,3-diazepan-2-one 
• 167824-61-5 (4R,5S,6S,7R)-4,7-dibenzyl-1-(cyclopropylmethyl)-5,6-dihydroxy-3-(5-hydroxypentyl)-1,3-diazepan-2-one 
• 167824-58-0 (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1-(3-hydroxybenzyl)-3-(5-hydroxypentyl)-1,3-diazepan-2-one 
• 167824-57-9 (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1-(6-hydroxyhexyl)-3-(naphthalen-2-ylmethyl)-1,3-diazepan-2-one 
• 167824-51-3 (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1-[4-(hydroxymethyl)benzyl]-3-(5-hydroxypentyl)-1,3-diazepan-2-one 
• 167824-49-9 (4R,5S,6S,7R)-1,4,7-tribenzyl-5,6-dihydroxy-3-(5-hydroxypentyl)-1,3-diazepan-2-one 
• 167824-48-8 (4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1-(5-hydroxypentyl)-3-(naphthalen-2-ylmethyl)-1,3-diazepan-2-one 
• 16782-44-8 tricyclo[4.1.0.0~2,4~]heptane 
• 16782-40-4 (1-adamantylamino)acetonitrile 
• 16782-39-1 tricyclo[3.3.1.1~3,7~]dec-1-ylhydrazine 
• 16782-30-2 3-cyclooctylpropan-1-ol 
• 167822-03-9 3,4-Furandiamine,tetrahydro-(9CI) 

Downstream Products

• 3058-98-8 sodium 4-hydroxy-3-[[3-(phenylsulphamoyl)-p-tolyl]azo]naphthalenesulphonate 
• 99576-15-5 Acid Black 210 
• 157577-99-6 Acid Black 234 

Recommend Products

• 74805-35-9  N-butyl-N-phenylbenzenesulfonamide 
• 109-65-9  1-bromo-butane 
• 4750-28-1  N-(4-chlorophenyl)benzenesulfonamide 
• 21226-30-2  2-chloro-1-(benzenesulfonylamino)benzene 
• 473-34-7  N,N-dichloro-p-toluenesulfonamide 
• 54437-69-3  N-ethyl-N-phenylbenzenesulfonamide 
• 74-96-4  ethyl bromide 
• 50-00-0  formaldehyd 
• 3027-01-8  N,N-dibenzoylaniline 
• 98-88-4  benzoyl chloride 
• 65236-40-0  N-phenyl-N-(phenylsulfonyl)benzamide 
• 39096-02-1  N-benzenesulfonyl-acetanilide 
• 75-36-5  acetyl chloride 
• 13360-57-1  dimethylamino sulfonyl chloride 

Related news

Discovery and optimization of Benzenesulfonanilide (cas 1678-25-7) derivatives as a novel class of 11β-HSD1 inhibitors09/24/2019

A novel series of benzenesulfonanilide derivatives of 11β-HSD1 inhibitors were identified via modification of the sulfonamide core of the arylsulfonylpiperazine lead structures. The synthesis, in vitro biological evaluation, and structure–activity relationship of these compounds are presented....detailed