40566-85-6

Basic information

• Product Name: 4-HYDRAZINO-BENZOIC ACID ETHYL ESTER HCL
• Synonyms: Benzoic acid, 4-hydrazino-, ethyl ester, Monohydrochloride;4-Hydrazino-benzoic acid ethyl ester hydrochloride;Ethyl 4-hydrazinylbenzoate hydrochloride
• CAS NO: 40566-85-6
• Molecular Formula: C₉H₁₂N₂O₂*ClH
• Molecular Weight: 0
• Mol File: 40566-85-6.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 4-HYDRAZINO-BENZOIC ACID ETHYL ESTER HCL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDRAZINO-BENZOIC ACID ETHYL ESTER HCL(40566-85-6)
• EPA Substance Registry System: 4-HYDRAZINO-BENZOIC ACID ETHYL ESTER HCL(40566-85-6)

Safety Data

• Hazardous Substances Data: 40566-85-6(Hazardous Substances Data)

Usage

General Description

4-Hydrazino-benzoic acid ethyl ester HCl is a chemical compound with the molecular formula C9H12ClN3O2. It is formed by the reaction of 4-hydrazinobenzoic acid with ethyl chloroformate in the presence of a base. 4-HYDRAZINO-BENZOIC ACID ETHYL ESTER HCL is commonly used as an intermediate in the synthesis of pharmaceuticals, dyes, and other organic compounds. It is also known to have potential biological activities, such as antiproliferative and antitumor effects. Due to its diverse applications in the field of organic chemistry and pharmaceuticals, 4-hydrazino-benzoic acid ethyl ester HCl is an important chemical compound with potential for further research and development.

Upstream product

• 94-09-7 p-aminoethylbenzoate 
• 64-17-5 ethanol 
• 619-67-0 4-Hydrazinobenzoic acid 
• 89101-11-1 3-(4-ethoxycarbonylphenyl)sydnone 
• 5798-75-4 Ethyl 4-bromobenzoate 

Downstream Products

• 374813-96-4 4-(3,5-bis-trifluoromethyl-pyrazol-1-yl)-benzoic acid ethyl ester 
• 7272-54-0 2-(5-Carboethoxy-1H-indol-3-yl)ethylamine 
• 924709-17-1 isonicotinic acid N'-4-[4-(4-bromophenylamino)-1,2,3-triazole-2-yl]benzoyl hydrazide 
• 924709-13-7 benzoic acid N'-4-(4-bromophenylamino-1,2,3-triazole-2-yl)benzoyl hydrazide 
• 924709-16-0 isonicotinic acid N'-4-(4-p-tolylamino-1,2,3-triazole-2-yl)benzoyl hydrazide 
• 924709-12-6 benzoic acid N'-4-(4-p-tolylamino-1,2,3-triazole-2-yl)benzoyl hydrazide 
• 895633-05-3 4-[4-(4-ethoxyphenylamino)-2H-1,2,3-triazol-2-yl]-N²-(4-chlorobenzoyl)benzhydrazide 
• 895633-04-2 4-[4-(4-ethoxyphenylamino)-2H-1,2,3-triazol-2-yl]-N²-(4-methylbenzoyl)benzhydrazide 
• 895633-09-7 4-[4-(4-bromophenylamino)-2H-1,2,3-triazol-2-yl]-N²-(4-chlorobenzoyl)benzhydrazide 
• 895633-07-5 4-[4-(4-fluorophenylamino)-2H-1,2,3-triazol-2-yl]-N²-(4-chlorobenzoyl)benzhydrazide 
• 895633-08-6 4-[4-(4-bromophenylamino)-2H-1,2,3-triazol-2-yl]-N²-(4-methylbenzoyl)benzhydrazide 
• 895633-06-4 4-[4-(4-fluorophenylamino)-2H-1,2,3-triazol-2-yl]-N²-(4-methylbenzoyl)benzhydrazide 
• 895633-03-1 4-[4-(4-methylphenylamino)-2H-1,2,3-triazol-2-yl]-N²-(4-chlorobenzoyl)benzhydrazide 
• 895633-02-0 4-[4-(4-methylphenylamino)-2H-1,2,3-triazol-2-yl]-N²-(4-methylbenzoyl)benzhydrazide 

Relevant articles and documents

Continuous flow synthesis of arylhydrazines: via nickel/photoredox coupling of tert -butyl carbazate with aryl halides

Nickel/photoredox catalyzed C-N couplings of hydrazine-derived nucleophiles provide a powerful alternative to Pd-catalyzed methods. This continuous-flow photochemical protocol, optimized using design of experiments, achieves these couplings in short residence times, with high selectivity. A range of (hetero)aryl bromides and chlorides are compatible and understanding of process stability/reactor fouling has been discerned. This journal is

BICYCLIC HETEROARYL INDOLE ANALOGUES USEFUL AS ROR GAMMA MODULATORS

The present disclosure is directed to compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein X, X1, M, R2, R3, R4, R5, m, n, and p are as defined herein, which are active as modulators of retinoid-related orphan receptor gamma t (RORγt). These compounds prevent, inhibit, or suppress the action of RORγt and are therefore useful in the treatment of RORγt mediated diseases, disorders, syndromes or conditions such as, e.g., pain, inflammation, COPD, asthma, rheumatoid arthritis, colitis, multiple sclerosis, neurodegenerative diseases and cancer.

Syntheses of 4-(5-oxo-1,2,4-triazol-3-yl)-sydnones and 4(4-arylamino-5-oxo-1,2,4-triazol-3-yl)-sydnones from sydnone derivatives and their fragments

4-(5-oxo-1,2,4-triazol-3-yl)-sydnones 11 and 4-(4-arylamino-5-oxo-1,2,4-triazol-3-yl)-sydnones 13 have been obtained from a-chloroformylarylhydrazine hydrochloride 2. Moreover, the intermediates, including 3, 4, 9 and 10, in this study are synthetically informative and valuable. It is also noteworthy that three reactants, 1, 2 and sydnonecarbaldehydes, were prepared from sydnone derivatives and their fragments. The oxidative cyclizations of sydnonecarbaldehyde semicarbazones 9 and carbazpnes 10 with two different oxidizing agents (Cu(ClO4)2 and Fe(ClO4)3) have been extensively examined. The reaction time and the yields of cyclizations were affected by the substituents of semicarbazones 9 and carbazones 10.