40580-73-2

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 100-16-3 4-nitrophenylhydrazone 
• 7732-18-5 water 
• 100-01-6 4-nitro-aniline 
• 636-99-7 4-nitrophenylhydrazine hydrochloride 

Downstream Products

• 76869-84-6 C₉H₉N₃O₅ 
• 149740-81-8 N-(p-nitrophenyl)carbonohydrazide 
• 1027429-26-0 ethyl 2-(4-aminophenyl)hydrazinecarboxylate 
• 19176-00-2 N'-[(2-(p-nitrophenyl)hydrazinyl)carbonyl]benzohydrazide 
• 80330-93-4 N'-(4-Nitro-phenyl)-N'-(2-oxo-cyclohexyl)-hydrazinecarboxylic acid ethyl ester 
• 149740-83-0 6-[(E)-2-(2,6-Dichloro-phenyl)-vinyl]-4-(4-nitro-phenylamino)-2H-[1,2,4]triazine-3,5-dione 
• 41780-25-0 2-(4-nitrophenyl)azo-1-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

An Efficient Synthesis of New 2-Aryl-5-phenylazenyl-1,3,4-oxadiazole Derivatives from N, N' -Diarylcarbonohydrazides

A series of new 1,3,4-oxadiazoles conjugated to aromatic substituents by an azo linker was synthesized in a four-step reaction sequence, involving cyclodehydration of a N, N' -diacylhydrazine fragment and dehydrogenation of the neighboring hydrazine fragm

Aerobic Oxidation of Alkyl 2-Phenylhydrazinecarboxylates Catalyzed by CuCl and DMAP

Recently, various fruitful organic reactions such as a catalytic Mitsunobu reaction were reported by virtue of alkyl 2-phenylazocarboxylates, however, the synthesis of alkyl 2-phenylazocarboxylates largely depended on the stoichiometric use of toxic oxidants. In this manuscript, an environment-friendly aerobic oxidative transformation of alkyl 2-phenylhydrazinecarboxylates to alkyl 2-phenylazocarboxylates is disclosed. The use of CuCl and DMAP system efficiently catalyzed the aerobic oxidation of alkyl 2-phenylhydrazinecarboxylates under mild conditions. The reaction rate of the present Cu-catalysis was much faster than that of the previously reported Fe-catalysis, and a variety of azo products were synthesized within 3 h. The present protocol was effective on larger scale. It was observed that the produced azo compound could undergo various reactions without isolation through one-pot sequential protocols.

Azocarbonyl-functionalized silanes

The invention provides azocarbonyl-functionalized silanes of the general formula I (R1)3-a(R2)aSi-RI-NH-C(O)-N=N-R4. They are prepared by a procedure in which in a first step hydrazine of t

N-(Propargyl)diazenecarboxamides for 'click' conjugation and their 1,3-dipolar cycloadditions with azidoalkylamines in the presence of Cu(II)

Propargyl functionalized diazenes 1 were prepared by two different approaches and were examined as alkyne click components in copper-catalyzed azide-alkyne cycloadditions (CuAAC) with 2-(azidomethyl)pyridine 5a and four α-azido-ω-aminoalkanes C2-C5 (5b-e)

Synthesis of photoaffinity probes for heme-containing proteins

Aryldiazenes with a second, photoactivatable, azide substituent on the aryl ring have been synthesized as active site probes for heme proteins of unknown active site structure. The probes include most of the possible isomers of the phenyl, naphthyl, and biphenyl ring systems. A selection of the probes has been shown to react with the model protein P450(cam) to give (arylazido)iron (Fe-ArN3) complexes, a prerequisite for subsequent affinity labeling of the protein.

Synthesis of some new 4,6-disubstituted-1,2,4-triazin-3,5(2H)diones and related compounds of potential antifungal activity

The synthesis of 4-substituted amino-6-styryl/alkyl/aryl-1,2,4-triazin-3,5(2H)diones (4a-d and 15) involving the cyclocondensation of N4-arylaminosemicarbazides (3a-d and 13) with some α-ketoacids is described. The behaviour of these triazinone

AN EFFICIENT METHOD FOR THE CONVERSION OF ARYLHYDRAZINES INTO 2-ARYL-4,4-DIALKYLSEMICARBAZIDES

Arylhydrazines are converted into 2-aryl-4,4-dialkylsemicarbazides by subsequent reaction with chloroformate, phosgene, dialkylamine, and alkaline hydrolysis.