40587-06-2Relevant academic research and scientific papers
Synthesis of chiral oxazolidinone derivatives through lipase-catalyzed kinetic resolution
Zhang, Yan,Zhang, Yang,Ren, Yansong,Ramstr?m, Olof
, p. 29 - 34 (2015)
The synthesis of enantioenriched oxazolidinone derivatives through lipase-catalyzed kinetic resolution is described. The synthesis comprised a two-step, cascade acylation in one pot, resulting in a range of oxazolidinone derivatives in good yields and exc
Compounds and Their Use for Treatment of Amyloid Beta-Related Diseases
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Page/Page column 28, (2012/05/21)
The present invention relates to novel compounds of formula (I) and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising said compounds, processes for making said compounds, and their use as medicaments for treatment and/or prevention of Aβ-related diseases.
HETEROCYCLIC CONTAINING AMINES AS KINASE B INHIBITORS
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Page/Page column 112, (2010/11/25)
The invention provides a compound of the formula (I) or a salt, solvate, tautomer or N-oxide thereof; for use as a PKB kinase inhibitor or PKA kinase inhibitor. In formula (I), A is a saturated hydrocarbon linker group; E is a monocyclic or bicyclic carbo
Sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones, preparation method, and medical use thereof
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Page/Page column 4, (2008/06/13)
The invention relates to sulfonyl-containing 3,4-diaryl-3-pyrrolin-2-ones compounds having formula (I) wherein R1 is selected from the group consisting of 4-methylsulfonyl, 4-aminosulfonyl, hydrogen, 2-, 3-, or 4-halogen, C1-C6
