40652-06-0

Usage

Uses

Used in Pharmaceutical Industry:
N-(1-Cyano-1-methylethyl)acetamide is used as a key intermediate for the synthesis of various drugs. Its role in the production of alpha-amino acid derivatives and beta-lactam antibiotics is particularly significant, contributing to the development of new pharmaceuticals with improved therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, N-(1-Cyano-1-methylethyl)acetamide is utilized as a precursor in the synthesis of pesticides. Its incorporation into these products enhances their effectiveness in controlling pests and diseases, thereby supporting agricultural productivity and crop protection.
Used in Organic Synthesis:
N-(1-Cyano-1-methylethyl)acetamide is employed as a versatile reagent in organic synthesis for the creation of various organic compounds. Its unique chemical structure and reactive properties allow for the development of new compounds with potential applications in different industries, including pharmaceuticals, agrochemicals, and materials science.

InChI:InChI=1/C6H10N2O/c1-5(9)8-6(2,3)4-7/h1-3H3,(H,8,9)

Upstream product

• 108-24-7 acetic anhydride 
• 70183-48-1 α-amino-isobutyraldehyde-oxime 
• 19355-69-2 2-amino-2-cyanopropane 
• 151-50-8 potassium cyanide 
• 67-64-1 acetone 

Downstream Products

• 5362-00-5 N-acetyl-α,α-dimethylglycine 
• 811-93-8 1,1-dimethylethylenediamine 

Relevant academic research and scientific papers

PROCESS FOR PRODUCING SUBSTITUTED AMINO ALCOHOLS

The present invention relates to a process for producing a compound of the formula (I) comprising at least the process step: a) reacting a compound of the formula (II) with hydrogen and water in the presence of at least one homogeneous transition metal catalyst TMC 1.

The Synthesis of Ketone-Derived Enamides by Elimination of HCN from Cyanoamides

Treatment of easily available ketone-derived cyanoamides with NaOtBu leads to enamides in a simple, scalable, and inexpensive one-step operation in good yield. Enamides not stabilized by conjugation or by inclusion in a ring can also be prepared. An E1cB mechanism consistent with all results and observations, is proposed. The Z geometry of the product enamide is highly favoured, and the regioselectivity can be directed by one′s choice of protecting group.

Synthesis of 4,4-Disubstituted 1,3-Thiazol-5(4H)-thiones

An easy synthesis for the 1,3-thiazol-5(4H)-thiones 5, a class of heterocycles which have hitherto only been available with difficulty, is described.Reaction of 3-amino-2H-azirines 25 with thiocarboxylic acids at 0 deg yields monothiodiamides of type 20 (Scheme 6) which, on treatment with Lawesson reagent at 100 deg, undergo thiation and cyclization to give 5 in good yield.

Water-soluble amine-linked polymeric colorants

Polymeric colorants comprising a hydrocarbon backbone and attached directly thereto through amine linkages, at least one water-solubilizing group and at least one optically chromophoric group are disclosed. In a preferred embodiment, the backbone is a saturated aliphatic hydrocarbon, the chromophore is an anthraquinone chromophore and the solubilizing group is a sulfonate or sulfamate residue.