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2-ethyl-2-(3-methoxyphenyl)butyronitrile, also known as α,α-Diethyl-3-methoxybenzeneacetonitrile, is an organic compound that serves as a crucial intermediate in the pharmaceutical industry. It is characterized by its unique molecular structure, which includes a nitrile group and a methoxyphenyl group, contributing to its reactivity and potential applications.

40692-21-5

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40692-21-5 Usage

Uses

Used in Pharmaceutical Industry:
2-ethyl-2-(3-methoxyphenyl)butyronitrile is used as an intermediate in the synthesis of Embutramide (E521010), a potent pharmaceutical sedative drug. Its role in the production process is essential, as it contributes to the drug's sedative properties and effectiveness in treating various conditions that require sedation.
Used in Analytical Studies:
In the field of analytical chemistry, 2-ethyl-2-(3-methoxyphenyl)butyronitrile is utilized for the detection of Embutramide in human blood samples. High-performance liquid chromatography (HPLC) with photodiode-array UV detection is employed to identify and quantify the presence of the sedative drug, providing valuable information for medical and forensic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 40692-21-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,6,9 and 2 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 40692-21:
(7*4)+(6*0)+(5*6)+(4*9)+(3*2)+(2*2)+(1*1)=105
105 % 10 = 5
So 40692-21-5 is a valid CAS Registry Number.

40692-21-5Relevant academic research and scientific papers

ALPHA, ALPHA DIALKYLBENZYL DERIVATIVES

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, (2008/06/13)

The invention concerns (alpha),(alpha)-dialkylbenzyl derivatives of the formula I wherein Ar1 is phenyl or naphthyl, or a 10-membered bicyclic heterocyclic moiety containing one or two nitrogen heteroatoms and optionally containing a further heteroatom selected from nitrogen, oxygen and sulphur; A1 is a direct link to X1 or is (1-3C)alkylene; X1 is oxy, thio, sulphinyl or sulphonyl; the phenylene group may optionally bear one or two substituents R3; each of R1 and R2, which may be the same or different, is (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl, fluoro-(1-4C)alkyl, phenyl or phenyl-(1-4C)alkyl, provided that both of R1 and R2 are not methyl or fluoromethyl; and Q is cyano, amino, nitro, formyl, (1-4C)alkoxy, thiazolyl or (2-4C)alkanoyl; or a pharmaceutically-acceptable salt thereof; processes for their manufacture; pharmaceutical compositions containing them and their use as 5-lipoxygenase inhibitors

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