617-80-1

Usage

Uses

Used in Pharmaceutical Industry:
2-ethylbutyronitrile is utilized as a solvent in the production of pharmaceuticals, facilitating the synthesis of various organic compounds. Its ability to dissolve a wide range of substances makes it a valuable asset in the development of new medications and pharmaceutical formulations.
Used in Chemical Synthesis:
As a starting material, 2-ethylbutyronitrile plays a crucial role in the synthesis of other chemicals. Its reactivity and compatibility with different chemical groups allow for the creation of a diverse array of compounds, expanding the horizons of chemical research and development.
Used in Agricultural Chemical Production:
2-ethylbutyronitrile serves as a chemical intermediate in the manufacturing process of agricultural chemicals. Its involvement in the synthesis of these products contributes to the development of effective solutions for crop protection and enhancement of agricultural yields.
Used in Plastics and Rubber Industry:
In the plastics and rubber sector, 2-ethylbutyronitrile is employed as a chemical intermediate. Its integration into the production process aids in the creation of various types of plastics and rubber materials, contributing to the versatility and performance of these materials in numerous applications.
Safety Considerations:
Given its classification as a hazardous chemical, 2-ethylbutyronitrile requires careful handling to mitigate potential risks associated with its toxicity and flammability. Proper safety measures and precautions should be implemented during its use to ensure the well-being of individuals and the environment.

InChI:InChI=1/C6H11N/c1-3-6(4-2)5-7/h6H,3-4H2,1-2H3

Upstream product

• 74-96-4 ethyl bromide 
• 109-74-0 propyl cyanide 
• 59346-52-0 2-ethyl-butyraldehyde dimethylhydrazone 
• 28118-34-5 Tetraethylbernsteinsaeuredinitril 
• 88-09-5 2-Ethylbutanoic acid 
• 68180-96-1 carbomethoxyhydrazone of 3-pentanone 
• 60-29-7 diethyl ether 
• 1619-56-3 ethyl 2-ethyl-2-cyanobutyrate 
• 925-90-6 ethylmagnesium bromide 
• 10467-10-4 ethylmagnesium iodide 
• 506-77-4 cyanogen chloride 
• 97-95-0 2-ethyl-1-butanol 
• 7664-41-7 ammonia 
• 75-05-8 acetonitrile 

Downstream Products

• 59346-54-2 2,2-diethyl-pent-4-enenitrile 
• 617-79-8 2-ethyl-N-butylamine 
• 100608-30-8 2-ethyl-2-benzyl-butyronitrile 
• 727428-26-4 2,2-diethyl-4-phenoxy-butyronitrile 
• 813-58-1 triethylacetic acid 
• 511-70-6 2-bromo-2-ethylbutanamide 
• 69096-41-9 N-(2-ethyl-butyl)-N'-phenyl-urea 
• 15595-78-5 2,2-Diaethyl-6-cyan-cyclohexan-1-on 
• 15595-80-9 3,3-Diaethyl-2-oxo-cyclohexan-1-carbonsaeureamid 
• 93309-48-9 2-Aethyl-2-<3-methoxy-phenyl>-butylamin 
• 92331-28-7 2-Aethyl-2-<2,5-dimethoxy-phenyl>-butylamin 
• 1372810-17-7 5-(pentan-3-yl)-1H-tetrazole 
• 1381757-98-7 C₂₂H₃₀ClNO₃S 
• 500310-68-9 2,2-diethyl-4-phenoxy-butylamine 

Relevant academic research and scientific papers

Bis-morpholinophosphorylchloride, a novel reagent for the conversion of primary amides into nitriles

Bis-morpholinophosphorylchloride (Bmpc), in the presence of a base, is an efficient dehydrating agent for both aromatic and aliphatic primary amides, and gives corresponding nitriles under mild conditions in god yields and purity. During the reaction the enantiomeric integrity remains intact.

Azaphthalocyanines with fused triazolo rings: Formation of sterically stressed constitutional isomers

The presented work deals with synthesis and isolation of constitutional isomers of triazolo-fused azaphthalocyanines. Distribution of the isomers did not follow the statistical calculations due to steric effects of the substituents preferring the least sterically stressed C4h isomer. The Royal Society of Chemistry 2012.

Effective transformation of aldoximes to nitriles by dehydration with 2-methylene-1,3-dioxepane in the presence of a Lewis acid catalyst

The dehydration of aldoximes with 2-methylene-1,3-dioxepane (MDO) proceeds smoothly in the presence of a catalytic amount of Lewis acid such as scandium(III) triflate to give corresponding nitriles in moderate to high yields under mild conditions.

On the oxidation of 3-ethylpentane under GifIV and Gif-orsay conditions

The oxidation of 3-ethylpentane under GifIV (and GoAggII) conditions affords, as major product, 3-acetylpentane and not diethylketone as previously reported. The discrepancy is explained by radical chain autoxidation in presence of a weak tertiary C - H bond.

α-ALKYLTHIO-NITRILES VIA CYANATION OF THIO-ACETALS AND KETALS

The reaction of thio-acetals or ketals with cyanotrimethylsilane in the presence of SnCl4 affords α-alkylthio-nitriles, which can be converted into a variety of other functional groups.

Substituent Effects on the C-C-Bond Strength, 2. The Thermal Stability of Tetrasubstituted Succinonitriles

Rate constants and activation parameters for the thermolysis reaction of ten, partly cyclic tetraalkylsuccinonitriles and of meso-2,3-dimethyl-2,3-diphenylsuccinonitrile were determined.Relationships between ΔG* (300 deg C), ΔH* and ΔS* of the thermolysis reaction on the one hand and the change in strain enthalpy during bond dissociation on the other are pointed out.A force field procedure for the estimation of the strain in α-cyanoalkyl radicals is presented.A quantitative separation of the steric and resonance effects responsible for the thermal dissociation pro cess was achieved successfully.A resonance energy of 5.3 kcal*mol-1 was deduced for tertiary α-cyanoalkyl radicals in agreement with the most recent literature data.