617-80-1

Basic information

• Product Name: 2-ethylbutyronitrile
• Synonyms: 2-ethylbutyronitrile;2-Ethylbutanenitrile
• CAS NO: 617-80-1
• Molecular Formula: C₆H₁₁N
• Molecular Weight: 97.15824
• EINECS: 210-531-1
• Mol File: 617-80-1.mol
• Article Data: 7

Chemical Properties

• Melting Point: -32.8°C (estimate)
• Boiling Point: 143.85°C
• Flash Point: 46°C
• Appearance: /
• Density: 0.7971
• Vapor Pressure: 4.85mmHg at 25°C
• Refractive Index: 1.4001
• CAS DataBase Reference: 2-ethylbutyronitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ethylbutyronitrile(617-80-1)
• EPA Substance Registry System: 2-ethylbutyronitrile(617-80-1)

Safety Data

• Hazardous Substances Data: 617-80-1(Hazardous Substances Data)

Usage

General Description

2-ethylbutyronitrile, also known as 2-ethylbutyronitrile, is a chemical compound with the molecular formula C6H11CN. It is a colorless liquid with a sweet, fruity odor. 2-ethylbutyronitrile is used as a solvent in the manufacture of pharmaceuticals and other organic compounds. It is also used as a starting material for the synthesis of other chemicals and as a chemical intermediate in the production of agricultural chemicals, plastics, and rubber. 2-ethylbutyronitrile is considered to be a hazardous chemical and should be handled with care due to its potential toxicity and flammability.

InChI:InChI=1/C6H11N/c1-3-6(4-2)5-7/h6H,3-4H2,1-2H3

Upstream product

• 97-95-0 2-ethyl-1-butanol 
• 1619-56-3 ethyl 2-ethyl-2-cyanobutyrate 
• 74-96-4 ethyl bromide 
• 75-05-8 acetonitrile 
• 52102-17-7 9-ethyl-9-borabicyclo[3.3.1]nonane 
• 3018-12-0 dichloroacetonitrile 
• 4358-72-9 methanesulfonic acid 1-ethylpropyl ester 
• 68180-96-1 carbomethoxyhydrazone of 3-pentanone 
• 143-33-9 sodium cyanide 
• 10467-10-4 ethylmagnesium iodide 
• 60-29-7 diethyl ether 
• 925-90-6 ethylmagnesium bromide 
• 28118-34-5 Tetraethylbernsteinsaeuredinitril 
• 88-09-5 2-Ethylbutanoic acid 

Downstream Products

• 59346-54-2 2,2-diethyl-pent-4-enenitrile 
• 6137-03-7 3-ethyl-2-pentanone 
• 4786-20-3 crotononitrile 
• 89580-25-6 2-ethyl-crotononitrile 
• 107-13-1 acrylonitrile 
• 500310-68-9 2,2-diethyl-4-phenoxy-butylamine 
• 1372810-17-7 5-(pentan-3-yl)-1H-tetrazole 
• 1381757-98-7 C₂₂H₃₀ClNO₃S 
• 92331-28-7 2-Aethyl-2-<2,5-dimethoxy-phenyl>-butylamin 
• 93309-48-9 2-Aethyl-2-<3-methoxy-phenyl>-butylamin 
• 15595-80-9 3,3-Diaethyl-2-oxo-cyclohexan-1-carbonsaeureamid 
• 15595-78-5 2,2-Diaethyl-6-cyan-cyclohexan-1-on 
• 69096-41-9 N-(2-ethyl-butyl)-N'-phenyl-urea 
• 511-70-6 2-bromo-2-ethylbutanamide 

Relevant articles and documents

Bis-morpholinophosphorylchloride, a novel reagent for the conversion of primary amides into nitriles

Bis-morpholinophosphorylchloride (Bmpc), in the presence of a base, is an efficient dehydrating agent for both aromatic and aliphatic primary amides, and gives corresponding nitriles under mild conditions in god yields and purity. During the reaction the enantiomeric integrity remains intact.

Effective transformation of aldoximes to nitriles by dehydration with 2-methylene-1,3-dioxepane in the presence of a Lewis acid catalyst

The dehydration of aldoximes with 2-methylene-1,3-dioxepane (MDO) proceeds smoothly in the presence of a catalytic amount of Lewis acid such as scandium(III) triflate to give corresponding nitriles in moderate to high yields under mild conditions.

On the oxidation of 3-ethylpentane under GifIV and Gif-orsay conditions

The oxidation of 3-ethylpentane under GifIV (and GoAggII) conditions affords, as major product, 3-acetylpentane and not diethylketone as previously reported. The discrepancy is explained by radical chain autoxidation in presence of a weak tertiary C - H bond.