406937-87-9

Upstream product

• 872-31-1 3-Bromothiophene 
• 71535-50-7 (S)-(+)-2-benzyl-1-(p-tolylsulfonyl)aziridine 
• 63-91-2 L-phenylalanine 
• 13505-32-3 N-tosyl-(S)-phenylalanine 
• 82495-70-3 (2S)-2-p-toluenesulfonamido-3-phenylpropanol 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant academic research and scientific papers

A new convenient approach to chiral β-aryl(heteroaryl)alkylamines

Chiral β-aryl(heteroaryl)alkylamines have been prepared from N-tosyl alkylaziridines via regiospecific nucleophilic ring opening and subsequent desulfonylation in good to excellent yields. The corresponding aziridines are easily obtained from commercially available (S)-α-amino acids, so this method is the first effective route to asymmetric β-aryl(heteroaryl)alkylamines.