4076-50-0

Basic information

• Product Name: 2-AMINO-4'-CHLOROBENZOPHENONE
• Synonyms: (2-aMino-4-chlorophenyl)(phenyl)Methanone
• CAS NO: 4076-50-0
• Molecular Formula: C₁₃H₁₀ClNO
• Molecular Weight: 231.6838
• Mol File: 4076-50-0.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-AMINO-4'-CHLOROBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4'-CHLOROBENZOPHENONE(4076-50-0)
• EPA Substance Registry System: 2-AMINO-4'-CHLOROBENZOPHENONE(4076-50-0)

Safety Data

• Hazardous Substances Data: 4076-50-0(Hazardous Substances Data)

Usage

Organic compound

2-Amino-4'-chlorobenzophenone

Primary use

Chemical filter in sunscreens and cosmetic products

Function

UV absorber

Protection

Shields skin from UVA and UVB radiation

Photostability

High

UV protection

Broad spectrum

Safety

Approved for use in cosmetics and skincare products by FDA and European Union

Skin compatibility

Excellent

Long-lasting protection against sun's rays

Yes

Upstream product

• 34999-47-8 N-(2-benzoyl-5-chlorophenyl)acetamide 
• 92161-52-9 6-chloro-3-hydroxy-3-phenylindolin-2-one 
• 158580-85-9 4-chloro-2-(phenylsulfonamido)benzoic acid 
• 38487-86-4 2-amino-4-chlorobenzonitrile 
• 98-80-6 phenylboronic acid 
• 100-58-3 phenylmagnesium bromide 
• 708-73-6 7-chloro-2-methyl-4H-3,1-benzoxazin-4-one 
• 31100-24-0 4-chloro-2-(4-methylphenylsulfonylamino)benzoic acid 
• 89-77-0 2-Amino-4-chlorobenzoic acid 
• 40928-13-0 4-chloroisatoic anhydride 
• 214971-18-3 4-chloroanthranilic acid N-methoxy-N-methylamide 
• 108-86-1 bromobenzene 
• 100-47-0 benzonitrile 
• 108-42-9 3-chloro-aniline 

Downstream Products

• 1073843-00-1 [4-(4-benzylpiperazin-1-yl)-2-aminophenyl]phenylmethanone 
• 120975-21-5 2-benzyl-5-chloroaniline 
• 3169-58-2 5-chloro-2-(1-phenylvinyl)aniline 
• 24400-58-6 6-chloro-3-phenyl-2,1-benzisoxazole 
• 150878-31-2 1-(2-amino-4-chlorophenyl)-1-phenylpentanol 

Relevant articles and documents

Asymmetric Synthesis of Hydroquinazolines Bearing C4-Tetrasubstituted Stereocenters via Kinetic Resolution of α-Tertiary Amines

A novel protocol for asymmetric synthesis of hydroquinazolines bearing C4-tetrasubstituted stereocenters has been achieved through kinetic resolution of 2-amido α-tertiary benzylamines via chiral phosphoric acid catalyzed intramolecular dehydrative cyclizations. This method gave access to both α-tertiary benzylamines and hydroquinazolines with broad scope and high enantioselectivities. An intriguing restricted rotation of the C-N bond was observed for hydroquinazoline products bearing C4-tetrasubstituted stereocenters.

One-Pot Synthesis of 2-Aminobenzophenones from 2-Alkynyl Arylazides Catalyzed by Pd and Cu Precursors

We describe a novel one-pot three-step reaction of 2-alkynyl arylazides through palladium-catalyzed formation of 3-hydroxy-3-phenylindolin-2-ones followed by hydrolysis of amide bonds and copper-catalyzed decarboxylation to give 2-aminobenzophenones. This synthetic method works well with various 2-alkynyl arylazides and affords the products in moderate to good yields under mild reaction conditions.

One-Pot Synthesis of Spirocyclopenta[ a]indene Derivatives via a Cascade Ring Expansion and Intramolecular Friedel-Crafts-Type Cyclization

A one-pot efficient synthetic approach for the rapid construction of spirocyclopenta[a]indene derivatives has been developed via an iodine-initiated cascade ring expansion and intramolecular Friedel-Crafts-type cyclization from propargyl alcohol-tethered alkylidenecyclobutanes under mild conditions with broad substrate scope. This cascade process can be elegantly conducted on a gram scale. A plausible reaction mechanism has been proposed on the basis of a series of deuterium labeling and control experiments.