34999-47-8

Basic information

• Product Name: N-(2-benzoyl-5-chlorophenyl)acetamide
• Synonyms: N-(2-benzoyl-5-chlorophenyl)acetamide
• CAS NO: 34999-47-8
• Molecular Weight: 273.719
• Mol File: 34999-47-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: N-(2-benzoyl-5-chlorophenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-benzoyl-5-chlorophenyl)acetamide(34999-47-8)
• EPA Substance Registry System: N-(2-benzoyl-5-chlorophenyl)acetamide(34999-47-8)

Safety Data

• Hazardous Substances Data: 34999-47-8(Hazardous Substances Data)

Upstream product

• 588-07-8 3-Chloroacetanilide 
• 100-52-7 benzaldehyde 
• 108-88-3 toluene 
• 108-42-9 3-chloro-aniline 
• 100-51-6 benzyl alcohol 
• 611-73-4 Benzoylformic acid 
• 708-73-6 7-chloro-2-methyl-4H-3,1-benzoxazin-4-one 

Downstream Products

• 25648-20-8 7-chloro-4-phenyl-1,4-dihydro-benzo[d][1,3]thiazine-2-thione 
• 35001-99-1 7-chloro-2-methylsulfanyl-4-phenyl-4H-benzo[d][1,3]thiazine 
• 25648-19-5 2-Amino-4-chlorobenzhydrol 
• 4076-50-0 2-amino-4-chlorobenzophenone 
• 106351-41-1 (4-Chloro-2-methylamino-phenyl)-phenyl-methanone 

Relevant articles and documents

Palladium-catalyzed direct oxidative ortho-acylation of anilides with toluene derivatives

Direct oxidative ortho-acylation reaction of anilides with toluene derivatives in the presence of palladium acetate using tert-butyl hydroperoxide as an oxidant was developed. A broad range of diaryl ketones was obtained in good to excellent yields (up to 95%). The plausible mechanism was also proposed.

A one-pot process for palladium catalyzed direct C-H acylation of anilines in water using a removable ortho directing group

A new mild, practical method for the synthesis of aminobenzophenone derivatives through a three step one-pot reaction sequence involving acylation of anilines, palladium catalyzed cross-dehydrogenative coupling of the formed anilides and the hydrolytic cleavage is reported. The full reaction sequence was performed under aqueous conditions.

Palladium-catalyzed direct ortho -acylation through an oxidative coupling of acetanilides with toluene derivatives

A facile ortho-acylation of acetanilides by a Pd-catalyzed oxidative C-H activation was developed in which low toxic, stable, and commercially available toluene derivatives were first used as acylation reagents by a tandem reaction to form o-acylacetanili