408327-64-0Relevant academic research and scientific papers
Carbonylative Sonogashira annulation sequence: One-pot synthesis of 4-quinolone and 4H-chromen-4-one derivatives
Ghosh, Prasanjit,Nandi, Aritra Kumar,Das, Sajal
, p. 2025 - 2029 (2018/04/25)
Carbonylative Sonogashira annulation sequence for one pot synthesis of 4-quinolone and 4H-chromen-4-one has been developed in presence of Pd-NHC catalyst. Substituted 2-iodoaniline and 2-iodophenol independently underwent in the carbonylative Sonogashira
One-Pot Allan–Robinson/Friedl?nder Route to Chromen-/Quinolin-4-ones through the Domino Acetylative Cyclisation of 2-Hydroxy-/2-Aminobenzaldehydes
Rai, Vijai K.,Verma, Fooleswar,Sahu, Ganeshwar P.,Singh, Manorama,Rai, Ankita
, p. 537 - 544 (2018/02/09)
The domino synthesis of 2-phenyl-4H-chromen-4-ones and quinolin-4-ones through acetylation of 2-hydroxy-/2-aminobenzaldehydes with α-haloketones followed by intramolecular oxa-/azaheterocyclisation is reported. This method represents a new extension of the Allan–Robinson and Friedl?nder reactions, and uses N-heterocyclic-carbene catalysis to construct the target molecules in good to excellent yields: 86–95 % for the chromen-4-ones, and 83–96 % for the quinolin-4-ones. This approach has the advantages of operational simplicity, ambient reaction conditions, and no by-product formation.
From Ketones, Amines, and Carbon Monoxide to 4-Quinolones: Palladium-Catalyzed Oxidative Carbonylation
Wu, Jiwei,Zhou, Yuchen,Wu, Ting,Zhou, Yi,Chiang, Chien-Wei,Lei, Aiwen
supporting information, p. 6432 - 6435 (2017/12/08)
A novel method of palladium-catalyzed oxidative carbonylation of ketones, amines, and carbon monoxide for the synthesis of 4-quinolones has been developed. This protocol provides a straightforward route to construct useful 4-quinolone derivatives from ine
Synthesis of 4-quinolones via a carbonylative sonogashira cross-coupling using molybdenum hexacarbonyl as a co source
?kerbladh, Linda,Nordeman, Patrik,Wejdemar, Matyas,Odell, Luke R.,Larhed, Mats
, p. 1464 - 1471 (2015/02/19)
A palladium-catalyzed CO gas-free carbonylative Sonogashira/cyclization sequence for the preparation of functionalized 4-quinolones from 2-iodoanilines and alkynes via two different protocols is described. The first method (A) yields the cyclized products
An efficient one-step synthesis of 2-arylquinolin-4(1H)-ones with the aid of a low-valent titanium reagent
Sun, Fang,Zhao, Xuan,Shi, Daqing
supporting information; experimental part, p. 5633 - 5635 (2011/11/06)
A short and facile synthesis of a series of 2-arylquinolin-4(1H)-ones was accomplished in good yields via the novel reductive cyclization of 2-nitrochalcones promoted by TiCl4/Zn. This method has the advantages of accessible starting materials,
