408359-16-0 Usage
Functional groups
Phenyl group
Trifluoromethyl group
Amino group bonded to the boron atom
Applications
Used as a building block in organic synthesis and medicinal chemistry
Particularly valuable in pharmaceutical and agrochemical development
Employed in the production of fluorescent dyes and sensors for biomolecule detection
Special properties
Ability to form stable complexes with diols and other Lewis bases
Utilized in the development of molecular recognition agents and catalysts
Check Digit Verification of cas no
The CAS Registry Mumber 408359-16-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,8,3,5 and 9 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 408359-16:
(8*4)+(7*0)+(6*8)+(5*3)+(4*5)+(3*9)+(2*1)+(1*6)=150
150 % 10 = 0
So 408359-16-0 is a valid CAS Registry Number.
408359-16-0Relevant academic research and scientific papers
Studies of palladium-catalyzed coupling reactions for preparation of hindered 3-arylpyrroles relevant to (-)-rhazinilam and its analogues
Ghosez, Leon,Franc, Cecile,Denonne, Frederic,Cuisinier, Claire,Touillaux, Roland
, p. 1827 - 1839 (2007/10/03)
Suzuki cross-coupling reactions of 3-pyrroleboronic acid derivatives with haloaromatics and the reverse process i.e., the coupling of 3-iodo(bromo)pyrroles with arylboronic acids have been investigated as a potential key step in the synthesis of (-)-rhazinilam and analogues. It was found that 3-iodo-2-formyl-1-tosylpyrroles efficiently coupled with a variety of arylboronic acids in the presence of PdCl2(dppf) as catalyst. This catalytic system is compatible with a broad spectrum of arylboronic acids - electron-rich, electron-poor, hindered, heterocyclic - which easily coupled with the pyrrole substrate.
