408365-67-3Relevant academic research and scientific papers
FORMULATION FOR ENHANCED TRANSDERMAL ABSORPTION OF DRUG
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Paragraph 0047-0048, (2019/04/14)
Provided is a transdermal formulation including a transdermal absorption enhancer including an aliphatic hydrocarbon derivative and a pyrrolidone derivative; and a benzene diamine derivative for preventing or treating dementia, Alzheimer's disease, and ha
COMPOSITION FOR PREVENTING OR TREATING HAIR LOSS INCLUDING BENZENE DIAMINE DERIVATIVE
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Paragraph 0057-0059, (2019/04/14)
Provided are a compound represented by the following Formula I, or a solvate, stereoisomer, or pharmaceutically acceptable salt thereof, and a composition for preventing or treating hair loss, the compound including the compound as an active ingredient:
COMPOSITION INCLUDING BENZENE DIAMINE DERIVATIVE FOR PREVENTING OR TREATING DEGENERATIVE BRAIN DISEASES
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Paragraph 0081; 0082, (2019/04/14)
Provided are a compound represented by the following Formula I-1 or I-2, and a composition for preventing or treating dementia or Alzheimer's disease, the composition including the compound and a pharmaceutically acceptable carrier:
Discovery, synthesis, and structure-activity relationship development of a series of N -4-(2,5-dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): Characterization of a novel positive allosteric modulator of the metabotropic glutamate receptor 4
Jones, Carrie K.,Engers, Darren W.,Thompson, Analisa D.,Field, Julie R.,Blobaum, Anna L.,Lindsley, Stacey R.,Zhou, Ya,Gogliotti, Rocco D.,Jadhav, Satyawan,Zamorano, Rocio,Bogenpohl, Jim,Smith, Yoland,Morrison, Ryan,Daniels, J. Scott,Weaver, C. David,Conn, P. Jeffrey,Lindsley, Craig W.,Niswender, Colleen M.,Hopkins, Corey R.
supporting information; experimental part, p. 7639 - 7647 (2012/01/05)
There is an increasing amount of literature data showing the positive effects on preclinical antiparkinsonian rodent models with selective positive allosteric modulators of metabotropic glutamate receptor 4 (mGlu4). However, most of the data ge
SUBSTITUTED 1,1,3,3-TETRAOXIDOBENZO[D][1,3,2]DITHIAZOLES AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION
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Page/Page column 108, (2010/08/09)
Compounds useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4) and methods of using the compounds.
