40841-62-1

Upstream product

• 874-60-2 4-methyl-benzoyl chloride 
• 17154-34-6 (trimethylsilyl)diphenylphosphine 
• 829-85-6 diphenylphosphane 

Downstream Products

• 603-35-0 triphenylphosphine 
• 18437-72-4 diphenyl (4‐fluorophenyl) phosphine 
• 734-60-1 (4-chlorophenyl)diphenylphosphane 
• 13406-28-5 <4-(trifluoromethyl)phenyl>diphenylphosphine 
• 896-89-9 (4-methoxyphenyl)diphenylphosphane 
• 1031-93-2 diphenyl(p-tolyl)phosphine 
• 13885-03-5 [1,1′-biphenyl]-4-yldiphenylphosphane 
• 1162-90-9 1-naphthyl(diphenyl)phosphine 
• 7579-70-6 diphenyl (3‐methylphenyl) phosphine 
• 5931-53-3 Diphenyl-o-tolylphosphin 
• 23415-66-9 (3-chlorophenyl)diphenylphosphine 
• 35035-62-2 diphenyl (2‐chlorophenyl) phosphine 
• 13885-09-1 [1,1′-biphenyl]-2-yldiphenylphosphane 
• 734-59-8 (4-bromophenyl)diphenylphosphane 

Relevant academic research and scientific papers

The carbonyl group tuned electron-deficient phosphorus ligands and their application in Rhodium catalyzed arylation to aldehydes

Acylphosphines, which could be efficiently prepared from acid chlorides and secondary phosphines, were developed as a type of carbonyl group tuned electron-deficient phosphorus ligand. They were found to be a kind of efficient ligand in Rhodium catalyzed arylation to aldehydes through accelerating the transmetalation process. Chiral acylphosphine ligands could be generated from carboxylic acids bearing the chiral framework correspondingly.

Palladium-Catalyzed C-P(III) Bond Formation by Coupling ArBr/ArOTf with Acylphosphines

Palladium-catalyzed C-P bond formation reaction of ArBr/ArOTf using acylphosphines as differential phosphination reagents is reported. The acylphosphines show practicable reactivity with ArBr and ArOTf as the phosphination reagents, though they are inert to the air and moisture. The reaction affords trivalent phosphines directly in good yields with a broad substrate scope and functional group tolerance. This reaction discloses the acylphosphines' capability as new phosphorus sources for the direct synthesis of trivalent phosphines.

The effect of an acylphosphine ligand on the rhodium-catalyzed hydrosilylation of alkenes

We synthesized a series of acylphosphines and investigated the hydrosilylation of alkenes that were catalyzed using RhCl3/acylphosphine. The results indicated that RhCl3/(diphenylphosphino) (phenyl)methanone exhibited higher activity as well as higher levels of β–adduct selectivity.

Palladium-catalyzed C–P(III) bond formation reaction with acylphosphines as phosphorus source

Palladium-catalyzed C–P(III) bond formation reaction employing acylphosphines as the phosphorus source was developed. Under the optimized conditions, acylphosphines could react with aryl halides directly affording trivalent phosphines in up to 94% yield.

Asymmetric synthesis of α-chiral hydroxyalkylphosphines by a catalytic enantioselective reduction of acylphosphines

Enantioselective reduction of acylphosphines, after precomplexation with borane, proceeded smoothly in the presence of a chiral oxazaborolidine catalyst and catecholborane. α-Hydroxyalkylphosphine products were obtained as phosphine-borane complexes in good yield and enantioselectivity. One of the products of the enantioselective reduction was successfully applied as an optically active phosphine ligand for asymmetric catalysis after suitable derivatization.