408523-53-5

Upstream product

• 6943-97-1 (m-methoxyphenyl)propyl bromide 
• 107-02-8 acrolein 
• 1826-67-1 vinyl magnesium bromide 
• 91152-86-2 4-(3'-methoxyphenyl)butyraldehyde 

Downstream Products

• 1823-11-6 6-m-Methoxyphenylhexan-3-on 
• 134329-65-0 1-(1-methoxy-4-methylbicyclo<2.2.2>oct-5-en-2-yl)-4-(3-methoxyphenyl)butan-1-one 
• 1444-59-3 6-(m-methoxyphenyl)hex-1-en-3-one 

Relevant academic research and scientific papers

Enantioselective Iridium-Catalyzed Allylic Cyclizations

A method for the enantioselective synthesis of carbo- and heterocyclic ring systems enabled through the combination of Lewis acid activation and iridium-catalyzed allylic substitution is described. The reaction proceeds with branched, allylic alcohols and carbon nucleophiles as well as heteronucleophiles to give a diverse set of ring systems in good yields and with high enantioselectivities. The utility of the method is highlighted by the asymmetric syntheses of erythrococcamides A and B.

Synthesis Based on Cyclohexadienes. V. A New Approach to the Synthesis of A-Ring Aromatic Steroids: a Formal Total Synthesis of (+/-)-Estrone

A new strategy for the construction of A-ring aromatic steroids which resulted in the formal total synthesis of estrone is described.Thus reaction of the adduct (9), obtained from 1-methoxy-4-methylcyclohexa-1,4-diene and acrolein, with 3-(m-methoxyphenyl