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1-Hexen-3-one, 6-(3-methoxyphenyl)-, also known as 6-(3-methoxyphenyl)-hexan-1-one, is a chemical compound with the molecular formula C12H16O2. It is a ketone characterized by a six-carbon chain and a phenyl group attached to the third carbon atom, featuring a methoxy substituent on the phenyl ring. 1-Hexen-3-one, 6-(3-methoxyphenyl)is known for its distinctive fruity and floral aroma, making it a valuable component in various industries.

1444-59-3

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1444-59-3 Usage

Uses

Used in Food and Beverage Industry:
1-Hexen-3-one, 6-(3-methoxyphenyl)is used as a flavoring agent in the food and beverage industry for its fruity and floral aroma, enhancing the taste and smell of various products.
Used in Perfumery:
In the perfume industry, 1-Hexen-3-one, 6-(3-methoxyphenyl)is utilized as a fragrance ingredient, contributing to the creation of complex and pleasant scents in perfumes and other scented products.
Used in Chemical Production:
1-Hexen-3-one, 6-(3-methoxyphenyl)is also used in the manufacture of other chemicals, serving as a building block or intermediate in the synthesis of various compounds.
Used in Pharmaceutical Research:
1-Hexen-3-one, 6-(3-methoxyphenyl)has been studied for its potential therapeutic properties, including antimicrobial and anti-inflammatory effects, indicating its possible use in the development of new drugs and treatments.
Used in Cosmetics Industry:
Given its pleasant aroma and potential therapeutic properties, 1-Hexen-3-one, 6-(3-methoxyphenyl)may also find applications in the cosmetics industry, where it could be used in the formulation of fragrances and other scented products with added benefits.

Check Digit Verification of cas no

The CAS Registry Mumber 1444-59-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,4 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1444-59:
(6*1)+(5*4)+(4*4)+(3*4)+(2*5)+(1*9)=73
73 % 10 = 3
So 1444-59-3 is a valid CAS Registry Number.

1444-59-3Relevant academic research and scientific papers

Synthesis of (-)-astrogorgiadiol

Taber,Malcolm

, p. 944 - 953 (2007/10/03)

Reaction of Rh2(S)-PTPA4 with the (R)-citronellol-derived α-diazo-β-ketoester 1 led to the formation of cyclic β-ketoester 2 in 95% yield and 48% diastereomeric excess. The purity of 2 was increased to >99% de after one crystallization. To demonstrate its utility in steroid total synthesis, the β-ketoester 2 was carried on to secosteroid (-)-astrogorgiadiol (3), a naturally occuring vitamin D analogue with antiproliferative properties.

Synthesis Based on Cyclohexadienes. V. A New Approach to the Synthesis of A-Ring Aromatic Steroids: a Formal Total Synthesis of (+/-)-Estrone

Rao, G. S. R. Subba,Banerjee, D. K.,Devi, L. Uma,Sheriff, Uma

, p. 187 - 203 (2007/10/02)

A new strategy for the construction of A-ring aromatic steroids which resulted in the formal total synthesis of estrone is described.Thus reaction of the adduct (9), obtained from 1-methoxy-4-methylcyclohexa-1,4-diene and acrolein, with 3-(m-methoxyphenyl

A HIGHLY CONVERGENT AND FLEXIBLE STRATEGY FOR THE SYNTHESIS OF A-RING AROMATIC STEROIDS

Mander, Lewis N.,Turner, John V.

, p. 3683 - 3686 (2007/10/02)

Using Hendrickson's criteria for systematic synthesis design, a strategy featuring a linear six carbon synthon (7) for bis-annulation has been devised for economic, flexible and highly convergent syntheses of A-ring aromatic steroids.

TOTAL SYNTHESIS OF STEROIDS. PART XV. A NOVEL METHOD OF SYNTHESIS OF β-AMINO KETONES AND VINYL KETONES AND ITS APPLICATION IN TOTAL SYNTHESIS OF ESTROGENS

Daniewski, Andrzej R.,Jinaraj, V. K.,Kocor, Marian

, p. 2243 - 2246 (2007/10/02)

A new method of synthesizing β-bromo ketones, vinyl ketones and β-N,N-dimethylamino ketones, starting from terminal olefines, diborane and 1-diazo-4-bromo-2-butanone has been described.The above method was utilized in total synthesis of estrogens.

Synthesis of gon-4-enes

-

, (2008/06/13)

1. A therapeutic composition having progestational activity comprising as active ingredient a 17-aliphatic carboxylic acid ester of 17α-ethynyl-18-methyl-19-nortestosterone and a pharmaceutical carrier for said compound.

Synthesis of 13-alkyl-gon-4-ones

-

, (2008/06/13)

The preparation of 13-methylgon-4-enes and novel 13-polycarbonalkylgon-4-enes by a new total synthesis is described. 13-Alkylgon-4-enes having progestational, anabolic and androgenic activities are prepared by forming a tetracylic gonane structure unsaturated in the 1,3,5(10),9(11) and 14-positions, selectively reducing in the B- and C-rings, and converting the aromatic A-ring compounds so-produced to gon-4-enes by Birch reduction and hydrolysis.

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