40874-54-2Relevant articles and documents
Formal Carbene C-H Bond Insertion in the Cu(I)-Catalyzed Reaction of Bis(trimethylsilyl)diazomethane with Benzoxazoles and Oxazoles
Wang, Shuai,Xu, Shuai,Yang, Cheng,Sun, Hanli,Wang, Jianbo
, p. 1809 - 1812 (2019)
A Cu(I)-catalyzed cross-coupling reaction of bis(trimethylsilyl)diazomethane and benzoxazoles/oxazoles is reported. A wide range of functional groups can be tolerated in this transformation. This reaction provides a new method to directly introduce a 1,1-bis(trimethylsilyl)methyl group into heteroaromatic C-H bonds. Subsequent transformations of 1,1-bis(trimethylsilyl)-methylated heteroaromatic compounds are also presented.
Synthesis of N-aryloxy-β-diketiminate ligands and coordination to zirconium, ytterbium, thorium, and uranium
Dulong, Florian,Thuery, Pierre,Ephritikhine, Michel,Cantat, Thibault
, p. 1328 - 1340 (2013/05/09)
Two examples of N-aryloxy-β-diketiminate dianions (11a,b) have been synthesized on a multigram scale, in four steps, from commercially available chemicals. The synthetic scheme relies on the sequential addition of 2,6-diisopropylaniline and 2-amino-4-tert-butylphenol (1a) (or 2-amino-4,6-di-tert-butylphenol (1b)) to acetylacetone, using Et 3OBF4 as an activation reagent. Both the nature of the activation reagent and the order of addition of the primary amines have a major impact on the outcome of the reaction, and acid catalysts (such as sulfuric acid or p-toluenesulfonic acid) lead to decomposition of the β-diketiminate backbone via formation of a benzoxazole derivative (3a,b). Using dianions 11a,b, mono- and bis(N-aryloxy-β-diketiminate) complexes of zirconium(IV), ytterbium(III), thorium(IV), and uranium(IV) have been synthesized (12-18), by salt metathesis reactions, and characterized by a combination of 1H/13C NMR spectroscopy, elemental analysis, and X-ray crystallography. The two ligands differ in their steric bulk and exhibit different coordination behaviors, which were rationalized on the basis of geometric considerations.
FLUORESCENT MEMBRANE INTERCALATING PROBES AND METHODS FOR THEIR USE
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Page/Page column 20-21, (2008/06/13)
The invention relates to a family of dyes which fluoresce in the UV-VIS, far red and near infrared wavelengths of the spectrum and possess asymmetric lipophilic alkyl chains. The dyes of the invention are soluble in commercially available membrane stainin