1199-46-8

Usage

Uses

Used in Chemical Synthesis:
2-Amino-4-tert-butylphenol is used as a reactant for the preparation of various intermediates and derivatives that hold significance in the field of chemistry and biology. It serves as a building block for synthesizing biologically important 2-(pyridyl)benzoxazole derivatives, which have potential applications in pharmaceuticals and other related areas.
Used in Organocatalysis:
In the field of organocatalysis, 2-Amino-4-tert-butylphenol is utilized to produce prolinamide phenols. These compounds act as efficient hydrophobic organocatalysts for direct asymmetric aldol reactions involving aldehydes and ketones in water, which are crucial processes in the synthesis of complex organic molecules and pharmaceuticals.
Used in Anion Sensitive Membrane Sensors:
2-Amino-4-tert-butylphenol is also used as a key intermediate in the preparation of N-(2-hydroxy-4-tert-butylphenyl)-acetamide. 2-Amino-4-tert-butylphenol is essential for the synthesis of uranylsalophene derivatives, which can be employed as selective receptors in anion-sensitive membrane sensors. These sensors have applications in environmental monitoring, chemical analysis, and other related fields.
Used in Polymer Synthesis:
Furthermore, 2-Amino-4-tert-butylphenol can be polymerized through electrochemical or chemical oxidative polymerization reactions to form Poly(2-amino-4-tert-butylphenol) [poly(2A-4TBP)]. This polymer has potential applications in various industries, including materials science, electronics, and coatings, due to its unique properties and characteristics.

InChI:InChI=1/C10H15NO/c1-10(2,3)7-4-5-9(12)8(11)6-7/h4-6,12H,11H2,1-3H3

Upstream product

• 15331-61-0 4-tert-Butyl-2-phenylazo-phenol 
• 3279-07-0 4-tert-butyl-2-nitrophenol 
• 98-54-4 para-tert-butylphenol 
• 100-34-5 benzene diazonium chloride 
• 7440-44-0 pyrographite 
• 1129-21-1 4-t-butyl-1,2-benzoquinone 
• 100-46-9 benzylamine 

Downstream Products

• 40874-54-2 5-(tert-butyl)-2-methylbenzo[d]oxazole 
• 79249-70-0 2-dimethylamino-4-t-butylphenol 
• 25847-85-2 1-(5-tert-Butyl-2-hydroxy-phenyl)-3-(4-chloro-phenyl)-urea 
• 25761-55-1 1-(4-Bromo-phenyl)-3-(5-tert-butyl-2-hydroxy-phenyl)-urea 
• 25761-44-8 1-(5-tert-Butyl-2-hydroxy-phenyl)-3-(4-chloro-3-trifluoromethyl-phenyl)-urea 
• 25761-39-1 1-(3,5-Bis-trifluoromethyl-phenyl)-3-(5-tert-butyl-2-hydroxy-phenyl)-urea 
• 17791-62-7 N-(5-(t-butyl)-2-hydroxyphenyl)acetamide 
• 53146-48-8 5-(tert-butyl)benzo[d]oxazole-2-thiol 
• 76825-99-5 (5-tert-Butyl-2-hydroxyphenylimino)triphenylphosphoran 
• 6529-93-7 4-tert-butyl-2-(2-chloro-acetylamino)-phenol 
• 106404-88-0 N,N'-di-(2-hydroxy-5-tert-butylphenyl)oxalamide 
• 479668-80-9 N-(2-hydroxy-5-t-butylphenyl)-5-bromofuran-2-carboxamide 

Relevant academic research and scientific papers

Record-high catalytic hydrogenated activity in nitroarenes reduction derived from in-situ nascent active metals enabled by constructing bimetallic phosphate

Herein, we report an excellent in-situ exsolution triggered hydrogenated catalyst F-Ni/Cu-P-RT started from bimetallic phosphate Ni/Cu-P-RT, affording an ultrafast catalytic hydrogenated rate (20 s even 5 s) in nitrophenol reduction. In the first catalytic cycle, we proved the enhanced catalytic reduction activity of bimetallic Ni/Cu-P-RT within 50 s compared to monometallic counterparts. The kinetics results revealed Ni/Cu-P-RT affords the reaction rate K of 2.85/4.23/6.6 min?1 at 20, 30, and 40 °C with the activation energy 32 kJ/mol. Impressively, the involved reaction induction period is visibly observed and interpreted by reconstruction and evolution of active metal during the reaction, but was eliminated through integrating two metal Cu-Ni by regulation of electronic band energy of phosphate from 4.1–3.5 eV. The nascent Cu and Ni nanoparticles as reaction-preferred active species were in-situ exsolved partially after adding NaBH4, triggering the resulted higher active and stable F-Ni/Cu-P-RT(20 s, 14.1 min?1) in later multiple cycles.

High Turnover Pd/C Catalyst for Nitro Group Reductions in Water. One-Pot Sequences and Syntheses of Pharmaceutical Intermediates

Commercially available Pd/C can be used as a catalyst for nitro group reductions with only 0.4 mol % Pd loading. The reaction can be performed using either silane as a transfer hydrogenating agent or simply a hydrogen balloon (μ1 atm pressure). With this technology, a series of nitro compounds was reduced to the desired amines in high chemical yields. Both the catalyst and surfactant were recycled several times without loss of reactivity.

HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND

Disclosed is a harmful arthropod control composition comprising, as an active ingredient, a fused heterocyclic compound represented by formula (1) [wherein A1 and A2 independently represent a nitrogen atom or the like; R1 and R4 independently represent a halogen atom or the like; R2 and R3 independently represent a halogen atom or the like; R5 and R6 independently represent a linear C1-C6 hydrocarbon group which may be substituted, or the like (provided that both R5 and R6 cannot represent a hydrogen atom simultaneously); and n represents 0 or 1]. The harmful arthropod control composition has an excellent efficacy to control harmful arthropods.

HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND

Disclosed is a harmful arthropod control composition comprising, as an active ingredient, a fused heterocyclic compound represented by formula (1) [wherein A1 and A2 independently represent a nitrogen atom or the like; R1 and R4 independently represent a halogen atom or the like; R2 and R3 independently represent a halogen atom or the like; R5 and R6 independently represent a linear C1-C6 hydrocarbon group which may be substituted, or the like (provided that both R5 and R6 cannot represent a hydrogen atom simultaneously); and n represents 0 or 1]. The harmful arthropod control composition has an excellent efficacy to control harmful arthropods.

COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS

The present invention provides: an arthropod pests control composition comprising, as active ingredients, a condensed heterocyclic compound and a neonicotinoid compound; a method for controlling arthropod pests which comprises applying effective amounts of a condensed heterocyclic compound and a neonicotinoid compound to the arthropod pests or a locus where the arthropod pests inhabit; and so on.

COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS

The present invention provides: an arthropod pests control composition comprising, as active ingredients, a condensed heterocyclic compound and a pyrethroid compound; a method for controlling arthropod pests which comprises applying effective amounts of a condensed heterocyclic compound and a pyrethroid compound to the arthropod pests or a locus where the arthropod pests inhabit; and so on.

COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS

The present invention provides: an arthropod pests control composition comprising, as active ingredients, a condensed heterocyclic compound and pyriproxyfen; a method for controlling arthropod pests which comprises applying effective amounts of a condensed heterocyclic compound and pyriproxyfen to the arthropod pests or a locus where the arthropod pests inhabit; and so on.

COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS

The present invention provides: an arthropod pests control composition comprising, as active ingredients, a condensed heterocyclic compound and pyridalyl; a method for controlling arthropod pests which comprises applying effective amounts of a condensed heterocyclic compound and pyridalyl to the arthropod pests or a locus where the arthropod pests inhabit; and so on.

COMPOSITION AND METHOD FOR CONTROLLING ARTHROPOD PESTS

The present invention provides: an arthropod pests control composition comprising, as active ingredients, a condensed heterocyclic compound and a diamide compound; a method for controlling arthropod pests which comprises applying effective amounts of a condensed heterocyclic compound and a diamide compound to the arthropod pests or a locus where the arthropod pests inhabit; and so on.

Regulatory molecules for the 5-HT3 receptor ion channel gating system

Substituted benzoxazole derivatives which possess a nitrogen-containing heterocycle at C2 are selective partial agonists of the 5-HT3 receptor. Alteration of substituents on the benzoxazole nucleus affords both agonist-like and antagonist-like compounds, and uniquely modifies the function of the 5-HT3 receptor ion channel gating system. SAR and corroborative computational docking study for these partial agonists successfully explained structure and function of the 5-HT3 receptor.