4088-84-0

Usage

Uses

Used in Pharmaceutical Industry:
3-Cyano-4-fluorobenzotrifluoride is used as a key building block for the synthesis of various drug molecules, contributing to the development of new pharmaceuticals due to its high reactivity.
Used in Agrochemical Production:
In the agrochemical sector, 3-Cyano-4-fluorobenzotrifluoride is utilized as an intermediate in the production of pesticides and herbicides, playing a significant role in the creation of effective crop protection agents.
Used in Specialty Chemicals Production:
3-Cyano-4-fluorobenzotrifluoride is also employed as an intermediate in the manufacturing process of specialty chemicals, highlighting its versatility and importance in the chemical industry's ability to produce a wide array of products.

InChI:InChI=1/C8H3F4N/c9-7-2-1-6(8(10,11)12)3-5(7)4-13/h1-3H

Downstream Products

• 612506-46-4 2-(2-nitrophenylamino)-5-trifluoromethylbenzonitrile 
• 660862-04-4 2-(4,5-difluoro-2-nitrophenylamino)-5-trifluoromethylbenzonitrile 
• 612506-48-6 2-(4-fluoro-2-nitrophenylamino)-5-trifluoromethylbenzonitrile 
• 693248-12-3 2-tert-butoxy-5-trifluoromethylbenzonitrile 
• 507239-99-8 2-(2-methyl-4-pyrrolidin-1-yl-quinolin-7-ylmethoxy)-5-trifluoromethyl-benzonitrile 
• 2250-53-5 3-amino-5-(trifluoromethyl)-1H-indazole 
• 146137-78-2 2-fluoro-5-trifluoromethylbenzaldehyde 
• 53984-37-5 2-(methylsulfanyl)-5-(trifluoromethyl)benzonitrile 
• 1215230-56-0 (S)-2-((1-methylpyrrolidin-2-yl)methoxy)-5-(trifluoromethyl)benzonitrile 
• 1269407-48-8 1,1-dimethylethyl [(1S)-2-({(3S)-1-[2-cyano-4-(trifluoromethyl)phenyl]-3-pyrrolidinyl}amino)-2-oxo-1-(2-thienylmethyl)ethyl]carbamate 
• 1269407-91-1 1,1-dimethylethyl [(1S)-2-({(3S)-1-[2-cyano-4-(trifluoromethyl)phenyl]-3-pyrrolidin-yl}amino)-1-methyl-2-oxoethyl]carbamate-d1 
• 1269408-33-4 N₁-{(3S)-1-[2-cyano-4-(trifluoromethyl)phenyl]-3-pyrrolidinyl}-L-alaninamide hydrochloride 
• 1269408-34-5 (2S)-2-amino-N-{(3S)-1-[2-cyano-4-(trifluoromethyl)phenyl]-3-pyrrolidinyl}butanamide hydrochloride 
• 1269408-61-8 N₁-{(3S)-1-[2-cyano-4-(trifluoromethyl)phenyl]-3-pyrrolidinyl}-3-(2-thienyl)-L-alaninamide hydrochloride 

Relevant academic research and scientific papers

Process for producing trifluoromethylbenzylamines

The invention relates to a process for producing a trifluotomethylbenzylamine represented by the following general formula (1), 1where each R independently represents a halogen selected from the group consisting of fluorine, chlorine, bromine and iodine, an alkyl group having a carbon atom number of 1-4, an alkoxy group having a carbon atom number of 1-4, an amino group, a hydroxyl group or a trifluoromethyl group, and n represents an integer from 0 to 4. The process includes hydrogenating a trifluoromethylbenzonitrile by hydrogen in an organic solvent in the presence of ammonia and a catalyst containing a platinum group element. This trifluoromethylbenzonitrile is represented by the following general formula (2), 2where R and n are defined as above. With this process, it is possible to obtain the trifluoromethylbenzylamine at an extremely high yield.

Process for producing trifluoromethylbenzylamines

The invention relates to a process for producing a trifluoromethylbenzylamine represented by the following general formula (1). This process includes hydrogenating a trifliuoromethylbenzonitrile represented by the following general formula (2) by hydrogen in an organic solvent in the presence of ammonia, using a Raney catalyst, where each R independently represents a halogen selected from the group consisting of fluorine, chlorine, bromine and iodine, an alkyl group having a carbon atom number of 1-4, an alkoxy group having a carbon atom number of 1-4, an amino group, a hydroxyl group or a trifluoromethyl group, and n represents an integer from 0 to 4, where R and n are defined as above. With this process, it is possible to obtain the trifluoromethylbenzylamine easily and inexpensively at an extremely high yield.