40896-45-5Relevant academic research and scientific papers
Synthesis of substituted-benzyl and sugar-modified analogues of 6-N-(4- nitrobenzyl)adenosine and their interactions with 'ES' nucleoside transport systems
Robins,Asakura,Kaneko,Shibuya,Jakobs,Agbanyo,Cass,Paterson
, p. 1627 - 1646 (2007/10/02)
Four classes of 6-X-benzylated purine nucleosides, (i) 6-N-(substituted- benzyl)adenosines, (ii) 6-N-(4-nitrobenzyl)adenine nucleosides with modified sugars, (iii) 6-N(S)-(4-azidobenzyl) derivatives of adenosine, 6-thioinosine, and 6-thioguanosine, and (iv) 6-N-{4-N-[acyl(sulfonyl)amino]benzyl} adenosines, were synthesized and their binding interactions with 'es-NT' (equilibrative, inhibitor-sensitive nucleoside transport) systems were studied. Several tight-binding analogues were found.
