40908-37-0

Basic information

• Product Name: 4-ACETAMIDO-2,2,6,6-TETRAMETHYLPIPERIDINE
• Synonyms: 4-ACETAMIDO-2,2,6,6-TETRAMETHYLPIPERIDINE;LABOTEST-BB LT00012694;n-(2,2,6,6-tetramethyl-4-piperidinyl)-acetamid;4-Acetylamino-2,2,6,6-Tertramethylpiperidine;N-(2,2,6,6-tetramethylpiperidin-4-yl)acetamide;N-(2,2,6,6-Tetramethylpiperidin-4-yl)-acetamid;N-(2,2,6,6-Tetramethyl-4-piperidinyl)acetamide;Acetamide, N-(2,2,6,6-tetramethyl-4-piperidinyl)-
• CAS NO: 40908-37-0
• Molecular Formula: C₁₁H₂₂N₂O
• Molecular Weight: 198.31
• EINECS: 255-137-0
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Piperidines
• Mol File: 40908-37-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 102-104 °C(lit.)
• Boiling Point: 161-163 °C7 mm Hg(lit.)
• Flash Point: 121℃
• Appearance: /
• Density: 0.96
• Vapor Pressure: 0.000286mmHg at 25°C
• Refractive Index: 1.4620 (estimate)
• PKA: 16.01±0.60(Predicted)
• CAS DataBase Reference: 4-ACETAMIDO-2,2,6,6-TETRAMETHYLPIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ACETAMIDO-2,2,6,6-TETRAMETHYLPIPERIDINE(40908-37-0)
• EPA Substance Registry System: 4-ACETAMIDO-2,2,6,6-TETRAMETHYLPIPERIDINE(40908-37-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 2
• Hazardous Substances Data: 40908-37-0(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 40908-37-0 differently. You can refer to the following data:
1. 4-Acetamido-2,2,6,6-tetramethylpiperidine is used in the preparation of antifungal selenium and sulfur derivatives of 2,2,6,6-tetramethylpiperidine. In addition it can be used as an antioxidant in the oxoammonium-salt form.
2. Reactant for synthesis of: Selenium and sulfur derivatives with antifungal activity Oxidants Alpha and beta-glycosidesReactant for reaction of nitroxyl radicals with metal carbonyls

General Description

4-Acetamido-2,2,6,6-tetramethylpiperidine is a piperidine derivative. Density of 4-acetamido-2,2,6,6-tetramethylpiperidine (N-(2,2,6,6-tetramethyl-4-piperidinyl)acetamide) has been reported.

InChI:InChI=1/C11H22N2O/c1-8(14)12-9-6-10(2,3)13-11(4,5)7-9/h9,13H,6-7H2,1-5H3,(H,12,14)

Upstream product

• 36768-62-4 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE 
• 64-19-7 acetic acid 
• 4168-79-0 4-hydroxyimino-2,2,6,6-tetramethylpiperidine 
• 826-36-8 2,2,6,6-Tetramethyl-4-piperidone 
• 108-24-7 acetic anhydride 
• 136708-43-5 4-acetylamino-2,2,6,6-tetramethyl-1-piperidinium acetate 

Downstream Products

• 14691-89-5 4-acetylamino-2,2,6,6-tetramethylpiperidine-N-oxyl 
• 36410-81-8 4-isothiocyanato-2,2,6,6-tetramethylpiperidine N-oxide 
• 14691-88-4 4-amino-2,2,6,6-tetramethyl-1-piperidine-1-oxyl 
• 14691-89-5 4-acetylamino-2,2,6,6-tetramethyl-1-piperidinoxy 

Relevant articles and documents

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A revised preparation of (4-Acetamido-2,2,6,6-tetramethylpiperidin-1-yl) oxyl and 4-acetamido-2,2,6,6-tetramethyl-1-oxopiperidinium tetrafluoroborate: Reagents for stoichiometric oxidations of alcohols

Revised preparations of (4-acetamido-2,2,6,6-tetramethylpiperidin-1-yl)oxyl and the corresponding oxoammonium salt, 4-acetamido-2,2,6,6-tetramethyl-1- oxoammonium tetrafluoroborate are presented together with some of the important properties of these two oxidizing reagents. Georg Thieme Verlag Stuttgart New York.

Synthesis of 2,2,6,6-tetramethylpiperidine derivatives

Diazotization of 4-amino-2,2,6,6-tetramethylpiperidine in acetic or sulfuric acid affords 2,2,6,6-tetramethyl-1,2,3,6-tetrahydropyridine in high yield. Under the same conditions, the corresponding nitroxyl radical transforms into 4-hydroxy-2,2,6,6-tetrame