40919-14-0

Upstream product

• 50415-73-1 methyl 2-(4-methoxyphenyl)propionate 
• 6274-50-6 methyl 2-(4-methoxyphenyl)-2-methylpropanoate 
• 2955-46-6 2-(4-methoxyphenyl)-2-methylpropanoic acid 

Downstream Products

• 1163705-55-2 (S)-2-methyl-pyrrolidine-1,2-dicarboxylic acid 2-amide 1-[(5-{2-[1-(4-methoxy-phenyl)-1-methyl-ethyl]-pyridin-4-yl}-4-methyl-thiazol-2-yl)-amide] 
• 141427-01-2 4-(2'-carboxy-2'-methylpropylmercapto)phenyl 2-(4'-methoxyphenyl)isobutyrate 
• 121990-17-8 N-chloro-N-methoxy-2-(4-methoxyphenyl)-2-methylpropionamide 
• 121989-29-5 (4-methoxyphenyl)-α,α-dimethyl-N-methoxyacetamide 

Relevant academic research and scientific papers

Chiral 2-Aryl Ferrocene Carboxylic Acids for the Catalytic Asymmetric C(sp3)-H Activation of Thioamides

Enantioselective C-H functionalization reactions using trivalent group 9 metals (Co, Rh, Ir) have been investigated mainly on the basis of the development of well-designed chiral cyclopentadienyl (Cp) ligands. Although it has recently been demonstrated th

Nickel-Catalyzed oxidative coupling of unactivated C(sp3)-H bonds in aliphatic amides with terminal alkynes

In this work, we demonstrated Ni-catalyzed oxidative coupling of unactivated C(sp3)-H bonds with terminal alkynes for construction of C(sp3)-C(sp) bonds to synthesize alkyl-substituted internal alkynes. Different amides exhibited good compatibility. Preliminary mechanistic studies were conducted to account for this alkynylation.

ORGANIC COMPOUNDS

The present invention relates to a compound of formula (I) (I) or a salt thereof, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol 3-kinase.

Organic Compounds

The present invention relates to compounds of formula I and its salts, wherein the substituents are as defined in the description, to compositions and use of the compounds in the treatment of diseases ameloriated by inhibition of phosphatidylinositol 3-kinase.