409305-55-1Relevant academic research and scientific papers
Tin powder-promoted diastereoselective allylation of chiral acylhydrazones
Peng, Xiansha,Wang, Ke-Hu,Huang, Danfeng,Wang, Juanjuan,Wang, Yalin,Su, Yingpeng,Hu, Yulai,Fu, Ying
, (2017/09/26)
An efficient method for the allylation of chiral acylhydrazones derived from aldehydes has been developed to give the corresponding allylic hydrazides in good yields and diastereoselectivities. The method uses a combination of tin powder and allylic bromide as allylation system, which avoids the use of toxic allylic stannanes while retaining their merits.
Dual activation in asymmetric allylsilane addition to chiral N-acylhydrazones: Method development, mechanistic studies, and elaboration of homoallylic amine adducts
Friestad, Gregory K.,Korapala, Chandra Sekhar,Ding, Hui
, p. 281 - 289 (2007/10/03)
Chiral N-acylhydrazones derived from commercially available 4-benzyl-2-oxazolidinone provide a rigid, conformationally restricted template to impart facial selectivity in additions to C=N bonds. In the presence of indium(III) trifluoromethanesulfonate [In
Asymmetric allylsilane additions to enantiopure N-acylhydrazones with dual activation by fluoride and In(OTF)3
Friestad,Ding
, p. 4491 - 4493 (2007/10/03)
A mild, convenient, and stereoselective addition of allylsilanes to enantiopure N-acylhydrazones occurs at room temperature upon complementary activation of both the allylsilane and the hydrazone (see scheme; OTf = trifluoromethanesulfonate). The reaction
