40943-37-1

Usage

Uses

Used in Pharmaceutical Synthesis:
N-Methoxycarbonyl-O-methylisourea is utilized as a reagent in the synthesis of pharmaceuticals, specifically for the preparation of 1,3-oxazolidin-2-ones. These intermediate compounds are vital for creating a variety of pharmaceuticals, highlighting the compound's importance in the development of new medications.
Used in Organic Synthesis:
In the realm of organic chemistry, N-Methoxycarbonyl-O-methylisourea serves as a versatile reagent, enabling the selective formation of 1,3-oxazolidin-2-ones from aldehydes and ketones. This selective reactivity is crucial for the synthesis of complex organic molecules, contributing to the advancement of organic chemistry.
Used in Peptide and Protein Derivatives Preparation:
N-Methoxycarbonyl-O-methylisourea is also employed in the preparation of peptide and protein derivatives, where its reactivity allows for the modification of these biologically significant molecules, potentially enhancing their properties or creating new functionalities.
Used in Functional Group Modification:
Furthermore, N-METHOXYCARBONYL-O-METHYLISOUREA is applied in the modification of functional groups in organic molecules, providing a means to alter the properties of these molecules and expand the scope of organic synthesis.
Overall, N-Methoxycarbonyl-O-methylisourea's applications span across various industries, including pharmaceuticals, organic chemistry, and biochemistry, due to its unique reactivity and ability to form important intermediate compounds.

InChI:InChI=1/C4H8N2O3/c1-8-4(7)6-3-9-2-5/h2,5H,3H2,1H3,(H,6,7)

Upstream product

• 29427-58-5 O-methylisourea hemisulfate 
• 79-22-1 methyl chloroformate 
• 24285-39-0 O-methylisourea hydrosulfate 
• 5329-33-9 o-methylisourea hydrochloride 
• 104-12-1 p-chlorphenylisocyanate 

Downstream Products

• 54965-21-8 Albendazole 
• 53626-78-1 methyl 4-(p-chlorophenyl)-N-methoxycarbonyl allophanimidate 
• 31430-15-6 flubendazole 
• 31431-39-7 mebendazole 
• 122558-91-2 methyl [5-[(3-chlorophenyl)(1H-imidazol-1-yl)methyl]-1H-benzimidazol-2-yl]carbamate 
• 136722-79-7 (+)-(S)-methyl <9-chloro-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)imidazo<4,5,1-jk><1,4>benzodiazepin-2-yl>carbamate 

Relevant academic research and scientific papers

Method of manufacturing using [...] compd. epinastine

PROBLEM TO BE SOLVED: To provide a method for producing epinastine via a new intermediate which is safely synthesizable at a low cost.SOLUTION: Epinastine is produced by reacting 5H-dibenz[b, e]azepine-6,11-dihydro-6-methanamine with an N-(iminoalkoxymethyl)carbamic acid ester to synthesize an N-(9,13-dihydro-1H-dibenz[c, f]imidazo[1,5-a]azepin-3-yl)-carbamic acid ester as an intermediate and treating the intermediate with an acid (process A). As an alternative, epinastine is produced by reacting an acid salt of 5H-dibenz[b, e]azepine-6,11-dihydro-6-methanamine with an N-(iminoalkoxymethyl)carbamic acid ester to synthesize an {imino[N-(5H-dibenz[b, e]azepin-6-yl)methylamino]methyl}carbamic acid ester as an intermediate and treating the intermediate with an acid (process B).

O-methyl-isourea carboxylic acid methyl ester preparation

The invention discloses a method for preparing O-methyl isourea methyl formate. According to the method, O-methyl isourea bisulfate and methyl chloroformate are put in the mixed solvent of chloroform-water or toluene-water and the like, and O-methyl isourea methyl formate is prepared under alkaline conditions. The method has no step of synthesizing O-methyl isourea sulfate, the production period is shortened, the energy consumption is reduced, the labor intensity of workers is reduced, and the production capacity is improved; the product cost is reduced and the environmental pollution is reduced due to no use of methanol and sodium hydroxide in the method; the water amount in the mixed solvent is strictly controlled, large water amount results in low yield due to large solubility of the product in water; small water amount results in difficult separation of the product due to poor dissolution of inorganic salts produced by the reaction; and the yield is improved by 1-2 percent.

Substituted 1,2,4,6-Thiatriazine 1,1-Dioxides, their Synthesis and Structure

N2-(Methoxycarbonyl)amidines 4 and analogously substituted O-(alkyl)isoureas 5 yield, on reaction with N-alkylsulfamic chlorides, sulfamides 6 and 7 which can be cyclized to give 1,2,4,6-thiatriazin-3-one 1,1-dioxides 8 or 9, respectively.Their structural assignment - with regard to the position of the acidic hydrogen - is supported by X-ray analysis of 9a.The compounds 8 and 9 show herbicidal activity.

Methods for increasing rice crop yields

Methods for increasing the yield of rice crops comprising applying thereto an allophanimidate such as methyl 4-(4-chlorophenyl)-N-methoxycarbonylallophanimidate or methyl 4-(4-chlorophenyl)-N-methylthiocarbonylallophanimidate to the seeds, seedlings, or the soil in which the seeds or seedlings are planted.

Methods for increasing rice crop yields

A method for increasing the yield of rice crops involving application of an s-triazinedione such as 3-(4-chlorophenyl)-6-methoxy-s-triazine-2,4(1H,3H)-dione to the seed, seedlings, or soil in which the seed or seedlings are planted.

1,3,5-Triazinediones

1,3,5-Triazinediones of the formula SPC1 Wherein X1, X2, R1, R2 and R3 are as hereinafter defined, are useful for the selective control of weeds in crops, e.g., corn. Many are also useful for altering plant flowering and plant sexual reproduction. Exemplary of the class of compounds are 3-isopropyl-6-methylthio-s-triazine-2,4(1H,3H)-dione, 3-(p-chlorophenyl)-6-methoxy-s-triazine-2,4(1H,3H)-dione.