40951-05-1

Basic information

• Product Name: (2E)-3-(1,3-benzodioxol-5-yl)-N,N-diethylprop-2-enamide
• Synonyms: (2E)-3-(1,3-Benzodioxol-5-yl)-N,N-diethylacrylamide; (E)-3-Benzo[1,3]dioxol-5-yl-N,N-diethyl-acrylamide; 2-propenamide, 3-(1,3-benzodioxol-5-yl)-N,N-diethyl-, (2E)-
• CAS NO: 40951-05-1
• Molecular Formula: C₁₄H₁₇NO₃
• Molecular Weight: 247.2897
• Mol File: 40951-05-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 423.1°C at 760 mmHg
• Flash Point: 209.7°C
• Density: 1.166g/cm³
• Vapor Pressure: 2.29E-07mmHg at 25°C
• Refractive Index: 1.58
• CAS DataBase Reference: (2E)-3-(1,3-benzodioxol-5-yl)-N,N-diethylprop-2-enamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-3-(1,3-benzodioxol-5-yl)-N,N-diethylprop-2-enamide(40951-05-1)
• EPA Substance Registry System: (2E)-3-(1,3-benzodioxol-5-yl)-N,N-diethylprop-2-enamide(40951-05-1)

Safety Data

• Hazardous Substances Data: 40951-05-1(Hazardous Substances Data)

Usage

General Description

The chemical (2E)-3-(1,3-benzodioxol-5-yl)-N,N-diethylprop-2-enamide is a compound with the molecular formula C17H21NO3. It is classified as an amide, containing a benzodioxole ring and a diethylpropenyl group. This chemical is commonly used in research and pharmaceutical applications, particularly in the development of drugs that target the central nervous system. Its specific properties and potential biological activities make it a valuable tool for understanding and treating various neurological conditions. However, due to its complex structure and potential for biological activity, (2E)-3-(1,3-benzodioxol-5-yl)-N,N-diethylprop-2-enamide should be handled and used with caution, following appropriate safety measures and guidelines.

Upstream product

• 109-89-7 diethylamine 
• 2373-80-0 3,4-(methylenedioxy)cinnamic acid 
• 120-57-0 piperonal 
• 2373-80-0 3,4-methylenedioxy-trans-cinnamic acid 
• 6080-83-7 <(N,N-Diethylcarbamoyl)methylidene>triphenylphosphorane 
• 2315-36-8 2-Chloro-N,N-diethylacetamide 

Relevant articles and documents

Piperine derivative as well as preparation method and application thereof

The invention provides a piperine derivative as well as a preparation method and an application thereof. The piperine derivative is a compound shown as a formula (I), or a salt thereof, or a stereoisomer thereof, or a hydrate thereof. The compound provided by the invention can effectively protect nerve cells and improve the survival rate of the nerve cells, so that the compound provided by the invention can effectively treat neurodegenerative diseases and can be used for preparing medicines for treating the neurodegenerative diseases.

Indium-mediated microwave-assisted one-pot synthesis of α,β-unsaturated amides

A stereoselective synthesis of α,β-unsaturated-N,N-diethyl amides was achieved by a one-pot reaction of triphenylphosphine, an aromatic aldehyde, and N,N-diethyl chloroacetamide in the presence of indium under microwave-assisted and solvent-free condition.

Microwave-assisted one-pot synthesis of α, β-unsaturated amides under solvent-free conditions

Under microwave-assisted solvent-free conditions a one-pot reaction of triphenylphosphine, an aldehyde and N, N-diethyl chloroacetamide in the presence of zinc dust affords α, β-unsaturated amides stereoselectively in good yield. In comparison with the co