4097-61-4

Usage

Uses

Used in Pesticide Industry:
3,4-dimethyl-2,6-dinitrophenol is used as an active ingredient in pesticides for its potent toxic effects on pests, providing effective control in agricultural settings.
Used in Dye Production:
In the dye industry, 3,4-dimethyl-2,6-dinitrophenol is used as a chemical intermediate for the synthesis of various dyes, contributing to the colorfastness and stability of the final products.
Used in Wood Preservation:
3,4-dimethyl-2,6-dinitrophenol is used as a wood preservative for its ability to protect wood from decay and insect infestation, enhancing the durability and longevity of wooden structures.
Used in Explosive Manufacturing:
In the production of explosives, 3,4-dimethyl-2,6-dinitrophenol is utilized for its high energy content and reactivity, making it a component in the formulation of certain types of explosives.
Used in Weight Loss (Illicit and Dangerous):
Although not approved and illegal for human consumption in many countries, 3,4-dimethyl-2,6-dinitrophenol has been illicitly used as a weight loss aid due to its ability to increase metabolic rate. However, its use in this context is extremely hazardous, leading to severe health effects such as hyperthermia, tachycardia, nausea, vomiting, and potentially death.
It is crucial to emphasize that due to the high toxicity of 3,4-dimethyl-2,6-dinitrophenol, it is considered a dangerous substance and should be handled with extreme caution to prevent accidental exposure or ingestion.

Upstream product

• 95-65-8 3,4-Dimethylphenol 
• 95-47-6 o-xylene 
• 95-64-7 4-amino-o-xylene 
• 18087-10-0 4,5-dimethyl-2-nitrophenol 
• 90916-26-0 Acetic acid 3,4-dimethyl-2,6-dinitro-phenyl ester 
• 40487-42-1 prowl 
• 7664-93-9 sulfuric acid 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 
• 3114-62-3 3,4-dimethyl-2-nitrophenol 
• 32590-94-6 3,4-dimethyl-4-nitrocyclohexa-2,5-dienone 

Downstream Products

• 40318-31-8 3,4-dimethyl-2,6-dinitroaniline 
• 160754-06-3 3,4-dimethyl-2,6-dinitroanisole 
• 125065-84-1 4-hydroxy-3,4-dimethyl-2,6-dinitrocyclohexa-2,5-dienone 

Relevant academic research and scientific papers

Nitration method for aryl phenol or aryl ether derivative

The invention relates to a nitration method for an aryl phenol or aryl ether derivative. The method comprises the steps of stirring an aryl phenol or aryl ether compound, nitrate, trimethylchlorosilane (TMSCl) and a copper salt in an acetonitrile solution in air at room temperature, simultaneously, monitoring extent of reaction through a TLC dot plate, removing a solvent from a mixture by a rotaryevaporator after a substrate is consumed completely, and carrying out purification through a silica-gel column, thereby obtaining a nitroolefin derivative. Meanwhile, the selective mono-nitration orbis-nitration of the substrate can be achieved through controlling equivalent weight of the nitrate. Compared with the prior art, the nitration method disclosed by the invention has the advantages that the consumption of strong-acid substances is avoided, the reaction conditions are mild, the yield is high, the applicable range of the substrate is wide, reaction activity is free of obvious attenuation after an amplified reaction, and an excellent yield is still obtained, so that the method has an obvious industrial application value.

Optimization of sulfonamide derivatives as highly selective EP1 receptor antagonists

A series of 4-[(2-{isobutyl[(5-methyl-2-furyl)sulfonyl]amino}phenoxy)methyl]benzoic acids and 4-({2-[isobutyl(1,3-thiazol-2-ylsulfonyl)amino]phenoxy}methyl)benzoic acids were synthesized and evaluated for their EP receptor affinities and EP1 receptor anta

Process for 3,4-disubstituted dinitroanilines

Preparation process for 3,4-disubstituted dinitroanilines of formula STR1 in which, R1 and R2, which are identical to or different from one another, represent a hydrogen atom, a C1 to C6 saturated, linear or branched alkyl radical, a C2 to C6 linear or br

Process and intermediate to prepare N-alkyl-3,4-dialkyl-2,6-dinitro-anilines

The intermediate STR1 wherein R is a lower alkyl group, is used to prepare a N-alkyl-3,4-dialkyl-2,6,-dinitro-aniline in a relatively simple, inexpensive and safe fashion, and with a high yield.

Novel process to prepare N-alkyl-3,4-dialkyl-2,6-dinitroanilines

A process is provided for preparing N-alkyl-3,4-dialkyl-2,6-dinitroanilines of the formula Wherein R1 is hydrogen, C1 to C6 straight or branched chain alkyl group; and, R2, R3 and R4 are independently C1 to C6 straight or branched chain alkyl group optionally substituted by one or more halogen groups, wherein a. 3,4-dialkyl phenol of the formula is selectively nitrated with nitric acid in a two phase system to form 3,4-dialkyl-2,6-dinitrophenol of the formula: b. the 3,4-dialkyl-2,6-dinitrophenol is alkylated with an alkylating agent in the presence of a base and a catalytic amount of a phase transfer catalyst chosen from the group consisting of, , (R')4Q X-, , wherein R' may be the same or different C1 to C16 straight or branched alkyl groups, benzyl, substituted benzyl; Qis N or P; and Xis CL, Br, I or HSO4; a macrocyclic ether and polyethylene glycols of formula, , HO - (CH2CH2O-)n-CH2CH2OH, , where n is an integer from 10 to 50, in an organic solvent to form 3,4-dalkyl-2,6-dinitro alkoxybenzene of the formula: where R5 is an alkyl group having 1 to 6 carbon atoms. c. the 3,4-dialkyl-2,6-dinitro alkoxybenzene is reacted with an amine of the formula where R1 and R2 are defined above, in the presence of a catalytic amount of base or halide to form N-alkyl-3,4-dialkyl-2,6-dinitroaniline. d. the N-alkyl-3,4-dialkyl-2,6-dinitroaniline is recovered.

The Nitration of 4-Methylphenol, 3,4-Dimethylphenol and 3,4,5-Trimethylphenol with Nitrogen Dioxide

Reaction of 4-methylphenol (1a) with excess nitrogen dioxide in either benzene or dichloromethane gives the 4-nitro dienone (2a) and the 2,6-dinitrophenol (5).Similar reactions of 3,4-dimethylphenol (1b) yields the 4-nitro dienone (2b), the 2,6-dinitrophe

INTRAMOLECULAR ELECTROPHILIC DISPLACEMENT OF ACYL BY NITRO GROUP DURING ATTEMPTED SYNTHESIS OF 3-NITROCOUMARINS

2-Hydroxyacetophenones undergo upon nitration in acetic acid a substitution of the acyl by nitro group followed by an intramolecular 1,3-acyl shift reminescent of a retro-Fries rearrangement to yield phenyl esters.