40994-01-2Relevant academic research and scientific papers
Olefination via Cu-Mediated Dehydroacylation of Unstrained Ketones
Dong, Guangbin,Xu, Yan,Zhou, Xukai
supporting information, p. 20042 - 20048 (2021/12/03)
The dehydroacylation of ketones to olefins is realized under mild conditions, which exhibits a unique reaction pathway involving aromatization-driven C-C cleavage to remove the acyl moiety, followed by Cu-mediated oxidative elimination to form an alkene between the α and β carbons. The newly adopted N′-methylpicolinohydrazonamide (MPHA) reagent is key to enable efficient cleavage of ketone C-C bonds at room temperature. Diverse alkyl- and aryl-substituted olefins, dienes, and special alkenes are generated with broad functional group tolerance. Strategic applications of this method are also demonstrated.
NOVEL OXABOROLE ANALOGS AND USES THEREOF
-
Paragraph 0266, (2018/09/21)
This application describes compounds, compositions, and methods which are useful in treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of a disease caused by a parasite.
STRUCTURE OF THE PRODUCTS FROM CONDENSATION OF AMIDRAZONES WITH MONOCARBONYL COMPOUNDS
Zelenin, K.N.,Khrustalev, V.A.,Sergutina, V.P.
, p. 822 - 829 (2007/10/02)
The structure of the products from the reaction of amidrazones with monocarbonyl compounds was invwstigated by spectral methods (IR, UV, (1)H and (13)C NMR). 1-Monosubstituted acetamidrazones and benzamidrazones form 1,3,5,5-tetrasubstituted 4,5-dihydro-1,2,4-triazoles, and the unsubstituted amidrazones form alkylidyne derivatives.
