410076-98-1

Upstream product

• 72261-44-0 1,2-O-isopropylidene-3-O-benzyl-4-C-(hydroxymethyl)-β-L-threo-pento-1,4-furanose 
• 410076-92-5 3-O-benzyl-5-O-(methanesulfonyl)-4-C-[[(methanesulfonyl)oxy]methyl]-1,2-O-isopropylidene-β-L-threo-pentofuranose 
• 146558-05-6 2-N-acetyl-6-O-(diphenylcarbamoyl)guanine 
• 410076-93-6 3-O-benzyl-1,2-di-O-acetyl-5-O-(methylsulfonyl)-4-C-(methylsulfonyloxymethyl)-α,β-L-threo-pentofuranose 
• 410076-97-0 9-(2-O-acetyl-3-O-benzyl-5-O-methanesulfonyl-4-C-methanesulfonyloxymethyl-α-L-threo-pentofuranosyl)-2-N-acetyl-6-O-(diphenylcarbamoyl)guanine 

Downstream Products

• 410076-99-2 9-(2-O-acetyl-3-O-benzyl-5-O-methanesulfonyl-4-C-(methanesulfonyloxymethyl)-α-L-erythro-pentofuranosyl)-2-N-acetyl-6-O-(diphenylcarbamoyl)guanine 
• 410077-00-8 2-N-acetyl-9-(3-O-benzyl-5-O-methanesulfonyl-4-C-(methanesulfonyloxymethyl)-α-L-erythro-pentofuranosyl)-6-O-(diphenylcarbamoyl)guanine 
• 410077-02-0 N-[9-(7-benzyloxy-1-hydroxymethyl-2,5-dioxa-bicyclo[2.2.1]hept-3-yl)-6-hydroxy-9H-purin-2-yl]-isobutyramide 
• 410077-01-9 (1R,3R,4S,7R)-7-benzyloxy-3-(guanin-9-yl)-1-hydroxymethyl-2,5-dioxabicyclo[2.2.1]heptane 

Relevant academic research and scientific papers

Synthesis of a base-protected α-L-LNA guanine nucleoside

Synthesis of (1R,3R,4S,7R)-7-hydroxy-1-hydroxymethyl-3-(2-N-isobutyroylguanin-9-yl)-2, 5-dioxabicyclo[2.2.1]heptane (12), a protected α-L-LNA guanine nucleoside, has been accomplished using a convergent synthetic strategy starting from 1,2-di-O-acetylfura

&α-L-ribo-Configured Locked Nucleic Acid (&α-L-LNA): Synthesis and Properties

The syntheses of monomeric nucleosides and 3'-O-phosphoramidite building blocks en route to α-L-ribo-configured locked nucleic acids (α-L-LNA), composed entirely of α-L-LNA monomers (α-L-ribo configuration) or of a mixture of α-L-LNA and DNA monomers (β-D