410077-02-0

Upstream product

• 410076-93-6 3-O-benzyl-1,2-di-O-acetyl-5-O-(methylsulfonyl)-4-C-(methylsulfonyloxymethyl)-α,β-L-threo-pentofuranose 
• 410077-01-9 (1R,3R,4S,7R)-7-benzyloxy-3-(guanin-9-yl)-1-hydroxymethyl-2,5-dioxabicyclo[2.2.1]heptane 
• 410076-97-0 9-(2-O-acetyl-3-O-benzyl-5-O-methanesulfonyl-4-C-methanesulfonyloxymethyl-α-L-threo-pentofuranosyl)-2-N-acetyl-6-O-(diphenylcarbamoyl)guanine 
• 410076-99-2 9-(2-O-acetyl-3-O-benzyl-5-O-methanesulfonyl-4-C-(methanesulfonyloxymethyl)-α-L-erythro-pentofuranosyl)-2-N-acetyl-6-O-(diphenylcarbamoyl)guanine 
• 410076-98-1 2-N-acetyl-9-(3-O-benzyl-5-O-methanesulfonyl-4-C-(methanesulfonyloxymethyl)-α-L-threo-pentofuranosyl)-6-O-(diphenylcarbamoyl)guanine 
• 410077-00-8 2-N-acetyl-9-(3-O-benzyl-5-O-methanesulfonyl-4-C-(methanesulfonyloxymethyl)-α-L-erythro-pentofuranosyl)-6-O-(diphenylcarbamoyl)guanine 

Relevant academic research and scientific papers

Synthesis of a base-protected α-L-LNA guanine nucleoside

Synthesis of (1R,3R,4S,7R)-7-hydroxy-1-hydroxymethyl-3-(2-N-isobutyroylguanin-9-yl)-2, 5-dioxabicyclo[2.2.1]heptane (12), a protected α-L-LNA guanine nucleoside, has been accomplished using a convergent synthetic strategy starting from 1,2-di-O-acetylfura