41013-30-3

Upstream product

• 951-87-1 rac-1,2-diphenylethylene-1,2-diamine 
• 123-54-6 acetylacetone 
• 90-02-8 salicylaldehyde 
• 29841-69-8 (S,S)-1,2-diphenyl-1,2-diaminoethane 
• 100-52-7 benzaldehyde 
• 14371-10-9 (E)-3-phenylpropenal 
• 119386-71-9 2,2’-((1R,2R)-1,2-diaminoethane-1,2-diyl)diphenol 
• 617-35-6 2-oxo-propionic acid ethyl ester 
• 951-87-1 meso-1,2-diphenyl-1,2-diaminoethane 
• 58519-80-5 meso-1,2-bis(2-hydroxyphenyl)-1,2-ethylenediamine 
• 5700-60-7 1,2-Diphenylethylenediamine 
• 119386-71-9 (SR,SR)-1,2-di-(2-hydroxyphenyl)-1,2-diaminoethane 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 89-95-2 2-methyl-benzyl alcohol 

Downstream Products

• 149580-33-6 chloro-[N,N'-bis(salicylidene)-1,2-diphenylethylenediaminato]manganese(III) 
• 897628-12-5 (C₆H₄(O)CHNCH(C₆H₅)CH(C₆H₅)NCHC₆H₄(O))CrCl 
• 1610435-17-0 C₂₉H₂₇N₂O₂⁽¹⁺⁾*Br^(1-) 
• 1610435-34-1 C₂₉H₂₇N₂O₂⁽¹⁺⁾*Cl^(1-) 
• 1035598-68-5 (S,S)-N,N'-bissalicyl-1,2-diamino-1,2-diphenylethane 
• 3190-01-0 N,N'-dibenzylidene-1,2-diphenylethane-1,2-diamine 
• 3190-01-0 racem-N,N'-dibenzylidene-bibenzyl-α,α'-diyldiamine 
• 51922-39-5 meso-N,N'-((E,E)-dibenzylidene)-bibenzyl-α,α'-diyldiamine 
• 951-87-1 rac-1,2-diphenylethylene-1,2-diamine 
• 3190-01-0 meso-α.α'-bis-benzylidenamino-bibenzyl 
• 84995-07-3 meso-2,2'-<(1,2-diphenylethylene)bis(iminomethylene)>diphenol 
• 951-87-1 meso-1,2-diphenyl-1,2-diaminoethane 

Relevant academic research and scientific papers

Salen-Ti(OR)4 complex catalysed trimethylsilylcyanation of aldehydes

Chiral selen-titanium complexes were found to be efficient catalysts for the enantioselective trimethylsilylcyanation of aldehydes. An enantioselectivity up to 87.1% e.e, was obtained by using 10mol% Ti(IV)-salen 2d as catalyst. The reaction mechanism was

Imine compound as well as synthesis method and application thereof

The invention provides an imine compound as well as a preparation method and application thereof, the imine compound is shown as a formula (III), and the imine compound is a traditional Chinese medicine intermediate. The method is realized in a grinding mode, heat supply of a heat source is not needed, a solvent is not needed, the grinding method saves time and cost, aftertreatment is simple, and industrial production is easy.

Three-Way Chemoselectivity Switching through Coupled Equilibria

Controlling the chemoselectivity of reactions operating on complex mixtures, including those found in biological and petrochemical feedstocks or in the primordial soup from which life emerged, is generally challenging. The selectivity of imine oxidation c

Mechanistic studies inform design of improved Ti(salen) catalysts for enantioselective [3 + 2] cycloaddition

Ti(salen) complexes catalyze the asymmetric [3 + 2] cycloaddition of cyclopropyl ketones with alkenes. While high enantioselectivities are achieved with electron-rich alkenes, electron-deficient alkenes are less selective. Herein, we describe mechanistic studies to understand the origins of catalyst and substrate trends in an effort to identify a more general catalyst. Density functional theory (DFT) calculations of the selectivity determining transition state revealed the origin of stereochemical control to be catalyst distortion, which is largely influenced by the chiral backbone and adamantyl groups on the salicylaldehyde moieties. While substitution of the adamantyl groups was detrimental to the enantioselectivity, mechanistic information guided the development of a set of eight new Ti(salen) catalysts with modified diamine backbones. These catalysts were evaluated with four electron-deficient alkenes to develop a three-parameter statistical model relating enantioselectivity to physical organic parameters. This statistical model is capable of quantitative prediction of enantioselectivity with structurally diverse alkenes. These mechanistic insights assisted the discovery of a new Ti(salen) catalyst, which substantially expanded the reaction scope and significantly improved the enantioselectivity of synthetically interesting building blocks.

Palladium (II)–Salan Complexes as Catalysts for Suzuki–Miyaura C–C Cross-Coupling in Water and Air. Effect of the Various Bridging Units within the Diamine Moieties on the Catalytic Performance

Water-soluble salan ligands were synthesized by hydrogenation and subsequent sulfonation of salens (N,N’-bis(slicylidene)ethylenediamine and analogues) with various bridging units (linkers) connecting the nitrogen atoms. Pd (II) complexes were obtained in reactions of sulfosalans and [PdCl4]2?. Characterization of the ligands and complexes included extensive X-ray diffraction studies, too. The Pd (II) complexes proved highly active catalysts of the Suzuki–Miyaura reaction of aryl halides and arylboronic acid derivatives at 80 ?C in water and air. A comparative study of the Pd (II)–sulfosalan catalysts showed that the catalytic activity largely increased with increasing linker length and with increasing steric congestion around the N donor atoms of the ligands; the highest specific activity was 40,000 (mol substrate) (mol catalyst × h)?1. The substrate scope was explored with the use of the two most active catalysts, containing 1,4-butylene and 1,2-diphenylethylene linkers, respectively.

Chiral and non-conjugated fluorescent salen ligands: AIE, anion probes, chiral recognition of unprotected amino acids, and cell imaging applications

Natural products are usually non-conjugated and chiral, but organic luminescent materials are commonly polycyclic aromatic molecules with extended π-conjugation. In the present work, we combine with the advantages of non-conjugation and chirality to prepare a series of novel and simple salen ligands (41 samples), which have a non-conjugated and chiral (S,S) and (R,R) cyclohexane or 1,2-diphenylethane bridge but display strong blue, green, and red aggregation-induced emission (AIE) with large Stokes shifts (up to 186 nm) and high fluorescence quantum yields (up to 0.35). Through hydrogen and halogen bonds, these flexible salen ligands can be used as universal anion probes and chiral receptors of unprotected amino acids (enantiomeric selectivity up to 0.11) with fluorescence quantum yields up to 0.29 and 0.27, respectively. Moreover, the effects of different chiral bridges on the molecule arrangement, AIE, and anion and chiral recognition properties are also explored, which provide unequivocal insights for the design of non-conjugated chiral and soft fluorescent materials.

Chiral heterobimetallic chains from a dicyanideferrite building block including a π-conjugated TTF annulated ligand

The π-conjugated tetrathiafulvalene (TTF) annulated ligand was introduced into a dicyanometallate for the first time, leading to the synthesis of the versatile redox-active dicyanideferrite building block [(n-Bu)4N][Fe(TTFbp)(CN)2] (

Group 4 metal complexes with new chiral pincer NHC-ligands: Synthesis, structure and catalytic activity

Chiral group 4 NHC-metal complexes were prepared in good yields by amine elimination from M(NR2)4 (M = Ti, Zr, Hf; R = Me, Et) and chiral pincer NHC-ligands, L4 (L4a and L4b), L5 and L6, which are derived from (S,S)-diphenyl-1,2-ethanediamine. Treatment of M(NR2)4 with 1 equiv. of L4 in THF gives, after recrystallization from a benzene solution, the chiral titanium amides (L4)Ti(NMe2)(Br)(THF) (7) and (L4)Ti(NMe2)(Cl)(THF) (11), zirconium amides (L4)Zr(NMe 2)(Br)(THF) (8), (L4)Zr(NEt2)(Br)(THF) (10), (L4)Zr(NMe2)(Cl)(THF) (12) and (L4)Zr(NEt2)(Cl)(THF) (14), and hafnium amides (L4)Hf(NMe2)(Br)(THF) (9) and (L4)Hf(NMe 2)(Cl)(THF) (13), respectively. Similarly, the reactions of L5 or L6 with 1 equiv. of M(NR2)4 yield the titanium amide (L6)Ti(NMe2)(Cl)(THF) (16), the zirconium amides (L5)Zr(NMe 2)(Cl)(THF) (15), (L6)Zr(NMe2)(Cl)(THF) (17) and (L6)Zr(NEt2)(Cl)(THF) (19), and the hafnium amide (L6)Hf(NMe 2)(Cl)(THF) (18), respectively. Complexes 7-19 were characterized by various spectroscopic techniques and elemental analyses. The molecular structures of 10 and 14-19 were also established by X-ray diffraction analyses, which represent the first example of the structurally characterized group 4 chiral NHC-metal complex. Furthermore, 7-19 are active catalysts for the polymerization of rac-lactide in the presence of isopropanol, leading to the heterotactic-rich polylactides. the Partner Organisations 2014.

Chirality transfer in magnetic coordination complexes monitored by vibrational and electronic circular dichroism

Magnetic coordination complexes based on Schiff bases are promising new molecular materials for electronics. Two μ-oxo FeIII dimeric complexes of enantiomers of Schiff base ligands (N,N′-(1R,2R)-1,2- diphenylethylenebis(salicylideneimine) (Hsu

Synthesis, crystal structures and antibacterial studies of oxidovanadium(IV) complexes of salen-type Schiff base ligands derived from meso-1,2-diphenyl-1,2-ethylenediamine

A series of new derivatives and previously reported Schiff base ligands and their oxidovanadium(IV) complexes were synthesized, characterized and tested as potential antibacterial agents against four human pathogenic bacteria. These N2O2 type Schiff base ligands were derived from the condensation of meso-1,2-diphenyl-1,2-ethylenediamine with different salicylaldehyde derivatives, and their metal complexes were obtained from the reaction of these ligands with bis(acetylacetonato)oxidovanadium(IV). Our studies showed that the metal complexes had moderate antibacterial activity, and this activity was higher than that of the free ligands against both Gram-positive and Gram-negative bacteria. Besides, it was found that the presence of more substituents on the ligands increases the antibacterial activities of both the free ligands and their complexes. The crystal structures of H2L4 and its corresponding complex VOL4 were determined by X-ray crystallography.