4107-65-7Relevant articles and documents
Envirocat EPZG(R), a new catalyst for the conversion of aldoximes into nitriles
Bandgar,Jagtap,Ghodeshwar,Wadgaonkar
, p. 2993 - 2998 (1995)
The conversion of aldoximes into nitriles was carried out at 100°C in the absence of a solvent using Envirocat EPZG(R) as a new solid supported catalyst.
Electrochemical Oxidative C?H Cyanation of Quinoxalin-2(1H)-ones with TMSCN
Li, Yifan,Liu, Ping,Sun, Peipei,Tong, Jinwen,Zhan, Yanling
supporting information, p. 2193 - 2197 (2021/07/22)
Both quinoxalin-2(1H)-ones and nitriles are valuable organic compounds, and it is an interesting task to introduce cyano into quinoxalin-2(1H)-ones. Herein a regioselective C?H cyanation of quinoxalin-2(1H)-ones was developed with a nucleophilic cyano source TMSCN under electrochemical oxidative conditions. This process allowed the synthesis of C3 cyanated quinoxalin-2(1H)-ones in moderate to excellent yields in the absence of transition-metal catalysts and organic hydroperoxides.
Method for converting aromatic aldehyde into aromatic nitrile by using sulfur powder promoted inorganic ammonium as nitrogen source (by machine translation)
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Paragraph 0046; 0047, (2020/09/12)
The invention discloses a method for converting aromatic aldehyde into aromatic nitrile. The method is conversion of high yield of aromatic aldehyde one-pot reaction of sulfur powder promoted inorganic ammonium as a nitrogen source into aromatic nitrile. The method has the advantages of no need of metal participation, no need of strong oxide, compatibility of reaction to air, easiness in amplification to a gram scale and the like, and overcomes the problems of harsh reaction conditions, complex operation, low functional group compatibility and the like in the prior art. (by machine translation)
Organophotoredox assisted cyanation of bromoarenes: via silyl-radical-mediated bromine abstraction
Shah, Sk. Sheriff,Shee, Maniklal,Singh, N. D. Pradeep
supporting information, p. 4240 - 4243 (2020/04/22)
The insertion of a nitrile (-CN) group into arenes through the direct functionalization of the C(sp2)-Br bond is a challenging reaction. Herein, we report an organophotoredox method for the cyanation of aryl bromides using the organic photoredox catalyst 4CzIPN and tosyl cyanide (TsCN) as the nitrile source. A photogenerated silyl radical, via a single electron transfer (SET) mechanism, was employed to abstract bromine from aryl bromide to provide an aryl radical, which was concomitantly intercepted by TsCN to afford the aromatic nitrile. A range of substrates containing electron-donating and -withdrawing groups was demonstrated to undergo cyanation at room temperature in good yields.