41085-43-2

Basic information

• Product Name: 2-Bromo-3-nitrotoluene
• Synonyms: 2-BROMO-3-NITROTOLUENE;2-Chloro-3-nitrotoluenem;1-Bromo-2-methyl-6-nitrobenzene;2-Bromo-3-methylnitrobenzene;2-Bromo-3-nitrotoluene,98%;2-Bromo-3-methylnitrobenzene, 2-Bromo-1-methyl-3-nitrobenzene;Benzene, 2-broMo-1-Methyl-3-nitro-;2-BroMo-3-nitrotoluene, 95+%
• CAS NO: 41085-43-2
• Molecular Formula: C₇H₆BrNO₂
• Molecular Weight: 216.03
• Product Categories: blocks;FluoroCompounds;NitroCompounds;Halogen toluene;Nitro Compounds;Nitro Compounds;Nitrogen Compounds;Organic Building Blocks
• Mol File: 41085-43-2.mol
• Article Data: 16

Chemical Properties

• Melting Point: 38-41 °C(lit.)
• Boiling Point: 135-136 °C8 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: Pale yellow/Low Melting Solid
• Density: 0.803 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.00576mmHg at 25°C
• Refractive Index: 1.6120 (estimate)
• Storage Temp.: Room temperature.
• Solubility: soluble in Methanol
• CAS DataBase Reference: 2-Bromo-3-nitrotoluene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-3-nitrotoluene(41085-43-2)
• EPA Substance Registry System: 2-Bromo-3-nitrotoluene(41085-43-2)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 41085-43-2(Hazardous Substances Data)

Usage

Chemical Properties

Pale yellow low melting solid

Uses

2-Bromo-3-nitrotoluene may be used in the preparation of unsymmetrical dimethyl dinitro biphenyl, via Ullmann reaction. It may be used as starting material in the synthesis of 10-methylfluoranthene.

General Description

Crystal structure of 2-bromo-3-nitrotoluene has been studied and the dihedral angle between the nitro group and the phenyl ring is reported to be 54.1(4)°.

InChI:InChI=1/C7H6BrNO2/c1-5-3-2-4-6(7(5)8)9(10)11/h2-4H,1H3

Upstream product

• 570-24-1 2-Methyl-6-nitroaniline 
• 95-46-5 2-methylphenyl bromide 
• 54879-20-8 2-bromo-3-methylaniline 
• 534-52-1 6-methyl-2,4-dinitrophenol 
• 7697-37-2 nitric acid 
• 95-48-7 ortho-cresol 
• 108-95-2 phenol 
• 59907-22-1 N-(2-methyl-6-nitrophenyl)acetamide 
• 120-66-1 N-(2-methylphenyl)acetamide 
• 13506-76-8 2-methyl-6-nitrobenzoic acid 

Downstream Products

• 859492-59-4 (+/-)-2-(2-methyl-6-nitro-phenyl)-thiophene-3-carboxylic acid 
• 758724-21-9 (+/-)-2,5-dimethyl-4-(2-methyl-6-nitro-phenyl)-furan-3-carboxylic acid 
• 146667-90-5 6-methyl-2-nitrostyrene 
• 54879-20-8 2-bromo-3-methylaniline 
• 5337-09-7 2-bromo-3-nitro-benzoic acid methyl ester 
• 82617-49-0 2-bromo-1-bromomethyl-3-nitrobenzene 
• 488118-31-6 (2-tert-butylphenyl)-(2-methyl-6-nitrophenyl)amine 
• 851229-19-1 2-(3-methylbut-2-enyl)-3-methylnitrobenzene 
• 41085-25-0 2-Hydroxy-6-methylphenylmethylsulfoxid 
• 41085-31-8 2-Amino-6-methylphenylmethylsulfoxid 
• 41085-41-0 2-Acetamido-6-methylphenylmethylsulfid 
• 41085-42-1 N-(2-Methanesulfinyl-3-methyl-phenyl)-acetamide 
• 1359964-03-6 N-(2-methyl-6-nitrophenyl)-2-(methylsulfanyl)-6-(morpholin-4-yl)pyrimidin-4-amine 

Relevant articles and documents

Novel method for preparing 3-iodo-2-bromotoluene

The invention discloses a novel method for preparing 2-bromo-3-iodotoluene, and belongs to the field of chemical synthesis. The method specifically comprises the following steps: a, reacting 2-amino-3-nitrotoluene serving as a raw material with a hydrobro

Synthetic method of aryl halide taking aryl carboxylic acid as raw material

A synthetic method of an aryl halide taking aryl carboxylic acid as a raw material is characterized in that a corresponding aryl halide is formed by carrying out substitution reaction on an aryl carboxylic acid compound and haloid salt MX in an organic solvent under the condition that oxygen, a silver catalyst, a copper additive and a bidentate nitrogen ligand exist, wherein M in MX represents alkali metal or alkaline earth metal, and X represents F, Cl, Br or I. Compared with a conventional aryl halide synthetic method, the synthetic method disclosed by the invention has the obvious advantages that reaction raw materials (comprising aryl carboxylic acid and MX) are cheap and easy to obtain, the using amount of a metal catalyst is small, pollution to the environment when the oxygen is used as an oxidant is the smallest, good tolerance to various functional groups on an aromatic ring is obtained, the yield is high, and the like. The synthetic method disclosed by the invention can be widely applied to synthesis in the fields of medicine, materials, natural products and the like in industry and academia.