41123-59-5

Basic information

• Product Name: 1,1-bis(2-chloroethylsulphonyl)methane
• Synonyms: 1,1-bis(2-chloroethylsulphonyl)methane;1,1'-[Methylenebis(sulfonyl)]bis(2-chloroethane);Bis[(2-chloroethyl)sulfonyl]methane;1,7-Dichloro-3,3,5,5-tetraoxo-3,5-dithiaheptane;Einecs 255-231-1;Ethane, 1,1'-(methylenebis(sulfonyl))bis(2-chloro-
• CAS NO: 41123-59-5
• Molecular Formula: C₅H₁₀Cl₂O₄S₂
• Molecular Weight: 269.1665
• EINECS: 255-231-1
• Mol File: 41123-59-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 531.2°Cat760mmHg
• Flash Point: 275.1°C
• Appearance: /
• Density: 1.53g/cm³
• Vapor Pressure: 7.83E-11mmHg at 25°C
• Refractive Index: 1.508
• CAS DataBase Reference: 1,1-bis(2-chloroethylsulphonyl)methane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-bis(2-chloroethylsulphonyl)methane(41123-59-5)
• EPA Substance Registry System: 1,1-bis(2-chloroethylsulphonyl)methane(41123-59-5)

Safety Data

• Hazardous Substances Data: 41123-59-5(Hazardous Substances Data)

Usage

General Description

1,1-bis(2-chloroethylsulphonyl)methane, also known as BCNU or Carmustine, is a chemotherapy drug used to treat certain types of cancer, including brain tumors, multiple myeloma, and lymphomas. It works by interfering with the growth and spread of cancer cells in the body. BCNU is classified as an alkylating agent, which means it attaches to DNA and disrupts the cell's ability to replicate, ultimately leading to cell death. Common side effects of BCNU treatment include nausea, vomiting, hair loss, and a decrease in blood cell counts. It is typically administered intravenously in a clinical setting under the supervision of a healthcare professional.

InChI:InChI=1/C5H10Cl2O4S2/c6-1-3-12(8,9)5-13(10,11)4-2-7/h1-5H2

Upstream product

• 84400-71-5 tetrakis(2-chloroethylthio)ethene 
• 74-85-1 ethene 
• 5799-68-8 methanedisulfonyl chloride 
• 41123-69-7 bis(2-hydroxyethylsulfonyl)methane 

Relevant articles and documents

Method for preparing intermediate bis(2-chloroethylsulfonyl) methane of bis(vinyl sulphone) methane

The invention relates to the field of organic chemical synthesis, in particular to a method for preparing high-purity bis(2-chloroethylsulfonyl) methane, and provides a method for preparing an intermediate bis(2-chloroethylsulfonyl) methane of bis(vinyl sulphone) methane.The method comprises the following steps that methanedisulfonyl dichloride and ethylene are adopted as raw materials, and under catalyzing of a lewis acid catalyst, reacting is carried out to generate bis(2-chloroethylsulfonyl) methane.According to the method for preparing bis(2-chloroethylsulfonyl) methane, methanedisulfonyl dichloride and ethylene are adopted as the raw materials, and bis(2-chloroethylsulfonyl) methane is obtained under the catalytic action of lewis acid or lewis acid load on a carrier.Compared with an existing production route, according to the method, the reaction steps are reduced, the production period is shortened, operation is easy, various poisonous and harmful reagents and reagents unfriendly to the environment are abandoned, environment friendliness is achieved, and a synthetic route with wide industrial prospects is achieved.

POLYSULFONYLETHYLENES. COMMUNICATION 1. SYNTHESIS OF TETRAKIS(ALKYL, ARYL)SULFONYLETHENES

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