4114-25-4

Usage

Chemical class

Urea derivatives

Usage

Ligand in coordination chemistry

Potential properties

Antitumor and anti-inflammatory

Molecular structure

Two benzylideneamino groups attached to a urea backbone

Preclinical studies

Shown to inhibit cancer cell growth and reduce inflammation

Applications

Medicinal chemistry and drug development

Research interest

Further exploration and investigation due to its potential in various fields

Upstream product

• 497-18-7 carbonodihydrazide 
• 100-52-7 benzaldehyde 
• 7732-18-5 water 
• 584-08-7 potassium carbonate 
• 94521-03-6 1-(diethoxyphosphoryl)-2-(phenylmethylidene)hydrazine 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 

Downstream Products

• 1617-16-9 hydrazine-N,N'-dicarboxylic acid bis-benzylidenehydrazide 
• 28867-76-7 benzaldehyde benzylidenehydrazone 
• 139355-70-7 2,4-dibenzylidenamino-1,2,4-thiadiazolidine-3,5-dione 
• 137678-64-9 1,3-bis(benzylideneamino)-2,4-imidazolidinedione 
• 262291-22-5 La(C₁₅H₁₄N₄O)Cl₃ 
• 262291-27-0 Pr(C₁₅H₁₄N₄O)Cl₃ 
• 13782-37-1 1,5-Dibenzyliden-2,4-dimethylcarbonohydrazid 
• 1361230-92-3 carbo-N'-benzylidene(N'-benzylidene-N-allylhydrazide) 
• 1361230-83-2 carbo-N'-benzylidene(N'-benzylidene-N-propylhydrazide) 
• 1361230-71-8 carbo-N'-benzylidene(N'-benzylidene-N-benzylhydrazide) 
• 1361230-69-4 carbo-di(N'-benzylidene-N-benzylhydrazide) 
• 87773-99-7 2,4-dibenzyl-6-phenyl-1,2,4,5-tetrazinan-3-one 
• 74809-00-0 1,4,5,6-Tetrahydro-2,4-dimethyl-6-phenyl-1,2,4,5-tetrazin-3(2H)-on 
• 1361230-94-5 2-methyl-6-phenyl-4-allyl-1,2,4,5-tetrazinan-3-one 

Relevant academic research and scientific papers

Olive-Shaped Organic Cages: Synthesis and Remarkable Promotion of Hydrazone Condensation through Encapsulation in Water

Two organic cages have been prepared in situ in water through the 2 + 3 hydrazone coupling of two pyridinium-derived trialdehydes and oxalohydrazide. The highly water-soluble cages encapsulate and solubilize linear neutral molecules. Such encapsulation ha

The photochromism, light harvesting and self-assembly activity of a multi-function Schiff-base compound based on the AIE effect

Aggregation-induced emission (AIE) luminogens with photochromic properties show strong potential in molecular switches, photo-controllable materials, photo-patterning, etc. In this paper one Schiff-base compound 1 exhibited reversible photo-controllable c

Efficient synthesis of 1,5-disubstituted carbohydrazones using K 2CO3 as a carbonyl donor

A novel reaction that generates 1,5-disubstituted carbohydrazones via the carbonylation of tosylhydrazones has been developed. For the first time, the inexpensive, readily available, environmentally friendly, and nongaseous potassium carbonate is used as

A hydrazine- and phosgene-free synthesis of tetrazinanones, precursors to 1,5-dialkyl-6-oxoverdazyl radicals

A complementary approach to published synthetic methods for tetrazinanones, precursors to verdazyl radicals, is described herein. This approach uses carbohydrazide, a commercially available reagent, as a common starting material. Unlike previous methods d

Synthesis, spectroscopic characterization and invitro antimicrobial investigation of some Hg(II) complex of carbohydrazone

The synthesis of novel mercury (II) complex with new ligands derived from Carbohydrazides has been reported. The complexes have general composition [HgL2X2], Where L= Carbohydrazone and X = Cl-, NO3-.

Green synthetic method for 1,5-disubstituted carbohydrazones

A green synthetic method for 1,5-disubstituted carbohydrazones is described. The reaction of dimethyl carbonate with hydrazine hydrate first gave carbohydrazide, which further reacted with various aromatic aldehydes or aliphatic ketones under solvent-free conditions to efficiently afford 1,5-disubstituted carbohydrazone. This protocol has the advantages of using nontoxic dimethyl carbonate as starting material, no use of organic solvents, short reaction time, high yield, and simple workup procedure. Copyright Taylor & Francis Group, LLC.