159329-38-1

Basic information

• Product Name: 1,4-Dioxaspiro[4.4]nonane-7-carbonitrile
• Synonyms: 1,4-Dioxaspiro[4.4]nonane-7-carbonitrile
• CAS NO: 159329-38-1
• Molecular Formula: C₈H₁₁NO₂
• Molecular Weight: 153.18
• Mol File: 159329-38-1.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,4-Dioxaspiro[4.4]nonane-7-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dioxaspiro[4.4]nonane-7-carbonitrile(159329-38-1)
• EPA Substance Registry System: 1,4-Dioxaspiro[4.4]nonane-7-carbonitrile(159329-38-1)

Safety Data

• Hazardous Substances Data: 159329-38-1(Hazardous Substances Data)

Usage

Type of compound

Spirocyclic organic compound

Structural features

Contains a dioxane ring and a carbonitrile group

Potential applications

Medicinal chemistry and pharmaceutical development

Biological activities

Unique biological activities due to its spirocyclic structure and carbonitrile group

Research status

Ongoing research in the field of medicinal chemistry and drug development

Upstream product

• 41171-91-9 3-oxocyclopentane-1-carbonitrile 
• 930-30-3 cyclopent-2-enone 
• 107-21-1 ethylene glycol 

Downstream Products

• 6947-04-2 ethyl 3,3-ethylenedioxycyclopentanecarboxylate 
• 163559-78-2 3-(diphenylhydroxymethyl)cyclopentanone ethylene ketal 
• 163559-77-1 3-phenethylcyclopent-2-en-1-one 
• 21414-81-3 cis-5,6-diphenylbicyclo<3.1.0>hexan-2-one 
• 21414-81-3 trans-5,6-diphenylbicyclo<3.1.0>hexan-2-one 
• 70239-00-8 3-benzhydrylcyclopent-2-en-1-one 
• 182298-14-2 3-Benzyl-3-(4-methyl-benzoyl)-cyclopentanone 
• 182298-12-0 3-(3-Methoxy-benzoyl)-cyclopentanone 
• 182298-13-1 3-(4-methoxybenzoyl)cyclopentan-1-one 
• 182298-11-9 3-(4-methylbenzoyl)cyclopentanone 
• 182298-10-8 3-(3-Methyl-benzoyl)-cyclopentanone 

Relevant articles and documents

D3 RECEPTOR AGONIST COMPOUNDS; METHODS OF PREPARATION; INTERMEDIATES THEREOF; AND METHODS OF USE THEREOF

Disclosed herein are novel compounds including dopamine D3 receptor agonists, compositions thereof, methods of use thereof, and processes of synthesizing the same. Further disclosed are D3R selective agonist compounds, specifically bitopic ligands comprising chirality.

Samarium diiodide-mediated pinacolization of diketones - II. Synthesis of polycyclic frameworks containing a cyclobutane-1,2-diol and a cyclopentane-1,2-diol

The title reaction has been applied to the synthesis of a variety of polycyclic networks. Scope and limitations of the procedure are evaluated.

Synthesis of bridgehead-substituted bicyclo[2.2.1]heptanes. Radical cyclization of an oxime ether and an α,β-unsaturated ester

The synthesis of bicyclo[2.2.1]heptanes with useful functionality at each bridgehead is achieved by radical cyclization of appropriately substituted 4-methylene- and 4-benzyloxyiminocyclohexylmethyl radicals. The latter process, for example, leads to a br